Results 101 to 110 of about 619,488 (302)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Particleboard properties from 2.0mm wood waste particle size in relation to different board density and resin content / Ahmad Hafizuddin Asha'ari [PDF]

open access: yes, 2016
Arise of logging activities cause lowing preserve of soil and the habitat for flora and fauna been reduced due increased demand for wooden materials every year.
Asha'ari, Ahmad Hafizuddin
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Multilevel structured low-density parity-check codes for AWGN and Rayleigh channels [PDF]

open access: yes, 2010
We propose a novel class of protograph low-density parity-check (LDPC) codes having a combinatorial rather than a random structure, which are termed multilevel-structured (MLS) LDPC codes. It is demonstrated that they posses a strikingly simple structure
Chen, Sheng   +2 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Effects of board density and mixing ratio on the physio-mechanical properties of cement-bonded particle board produced from Ceiba pentandra Sawdust [PDF]

open access: yes, 2019
The study evaluated the physical and mechanical properties of cement–bonded particleboards produced from the sawdust of Ceiba pentandra. The production variables investigated were two board densities (1300kg/m3 and 1200kg/m3) and three different mixing ...
Ayanleye, Samuel Oluwafemi; University of British Columbia, Vancouver   +4 more
core  

Design and Realization of High-density FDR Interconnection Switch Board [PDF]

open access: yes, 2016
Aiming at the deficiency of signal integrity for the Printed Circuit Board(PCB) design of high-density Fourteen Data Rate(FDR) interconnection switch,this paper proposes a solution scheme in the aspects of material selection,stackup assignment,wiring and
LIU Lu,CAO Yuesheng,DUO Ruihua
core   +1 more source

Decay Resistance of Medium Density Fibreboard (MDF) Made from Pineapple Leaf Fiber

open access: yesJournal of Mathematical and Fundamental Sciences, 2015
Medium density fiberboard (MDF) production is increasing due to the development of manufacturing technologies. MDF products are utilized for traditional wood applications that require fungal resistance.
Yuliati Indrayani   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

High Power Density On-Board Charger Featuring Power Pulsating Buffer [PDF]

open access: yes
Power electronics plays a key role in electric vehicle technology in areas such as the battery charging and managing, dc distribution and motor drive systems, among others.
Hector Sarnago   +3 more
core   +1 more source

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