Results 101 to 110 of about 4,351,903 (305)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

PENGUJIAN SIFAT FISIS-MEKANIS DAN NONDESTRUKTIF METODE GELOMBANG SUARA PAPAN WOL SEMEN BERKERAPATAN SEDANG-TINGGI BAMBU BETUNG (DENDROCALAMUS ASPER)

open access: yesJurnal Ilmu Pertanian Indonesia, 2012
Cement board is a composite wood product has advantages such as fire resistance, termite, water resistant, and has good sound insulation properties. Bamboo is suitable material that can be used as a raw material of cement board.
Lina Karlinasari   +4 more
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Utilização de madeiras de Eucalyptus grandis E Eucalyptus dunnii para produção de painéis de partículas orientadas – OSB

open access: yesCiência Florestal, 2008
This study was developed to evaluate the feasibility of OSB manufacturing using woods of Eucalyptus grandis and Eucalyptus dunnii. Boards with nominal density of 0,70 g/cm³ and 1,0 g/cm³ were manufactured in laboratory, using 100% of wood particles from ...
Setsuo Iwakiri   +3 more
doaj  

Columbia Accident Investigation Board Report: Volume 5. Other Significant Documents

open access: yes, 2003
Fifth volume of the final report produced by the Columbia Accident Investigation Board including documents produced by NASA and other organizations that were provided to the Columbia Accident Investigation Board in support of its inquiry into the ...
Columbia Accident Investigation Board
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Annual report of the Board of Arbitration, State of Illinois.

open access: yes, 1916
Mode of access: Internet.Continues: Illinois. State Board of Arbitration.
Illinois. State Board of Arbitration.
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

PEMANFAATAN LIMBAH BATANG UBI KAYU DAN PLASTIK SEBAGAI BAHAN BAKU PEMBUATAN PAPAN PARTIKEL

open access: yesJournal of Research and Technology, 2020
Particle board consists of sheets of material made from wood chips or materials containing lignocellulose such as flakes and strands to be joined by using a binder and by providing various aids such as heat and press.
Laurentius Urip Widodo   +2 more
doaj  

Columbia Accident Investigation Board Report: Volume 5 Appendices G.1 - G.9. Other Significant Documents

open access: yes, 2003
Fifth volume of the final report produced by the Columbia Accident Investigation Board including documents produced by NASA and other organizations that were provided to the Columbia Accident Investigation Board in support of its inquiry into the ...
Columbia Accident Investigation Board
core  

Home - About - Disclaimer - Privacy