Results 81 to 90 of about 1,369,533 (295)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Karakteristik Papan Semen Partikel Dari Limbah Pabrik Kuas [PDF]

open access: yes, 2016
This study aims to investigate the properties of cement particle board from brush factory waste using Portland Puzzolan Cement (PPC) as adhesive. Characteristics of cement particle board was studied consists of: density, heavy boards, thickness swelling,
Amalia, A. (Amalia)   +1 more
core  

On-board propulsion system analysis of high density propellants [PDF]

open access: yes34th AIAA/ASME/SAE/ASEE Joint Propulsion Conference and Exhibit, 1998
The impact of the performance and density of on-board propellants on science payload mass of Discovery Program class missions is evaluated. A propulsion system dry mass model, anchored on flight-weight system data from the Near Earth Asteroid Rendezvous mission is used. This model is used to evaluate the performance of liquid oxygen, hydrogen peroxide,
openaire   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

X-Ray Absorption Analysis of MCG-6-30-15: Discerning Three Kinematic Systems

open access: yes, 2009
By analyzing the X-ray spectrum of MCG-6-30-15 obtained with the HETG spectrometer on board the Chandra Observatory, we identify three kinematically distinct absorption systems; two outflow components intrinsic to MCG-6-30-15, and one local at z = 0. The
Badnell   +32 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

SIFAT PAPAN SEMEN SABUT KELAPA

open access: yesJurnal Penelitian Hasil Hutan (Journal of Forest Products Research), 2017
The report  deals  with  laboratory  tests  on  the properties   of cement board  made  from   coconut husk bonded  with  Portland  cement. The test  includes  board  density,   moisture   content.   thickness reduction due to  and bending strength. The 
Rozak Memed   +2 more
doaj   +1 more source

Kualitas Papan Partikel Dari Campuran Sabut Kelapa Dan Partikel Mahoni Dengan Berbagai Variasi Kadar Perekat Phenol Formaldehida [PDF]

open access: yes, 2015
Coco fiber and mahogany can be used as raw material for the manufacture of particle board. Quality of particle board was affected by several things. One of them was affected by particle's composition and adhesive levels.
Fransiskus, H. (Heber)   +2 more
core  

Graphene Oxide as an Optimal Candidate Material for Methane Storage

open access: yes, 2015
Methane, the primary constituent of natural gas, binds too weakly to nanostructured carbons to meet the targets set for on-board vehicular storage to be viable.
Chouhan, Rajiv K.   +2 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Home - About - Disclaimer - Privacy