Results 71 to 80 of about 1,369,533 (295)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

A deep X-ray observation of supernova remnant G304.6+0.1 (Kes 17) with Suzaku

open access: yes, 2012
In this paper, we present the analysis of a deep (99.6 ks) observation of G304.6 + 0.1 with the X-ray Imaging Spectrometer on board {\it Suzaku} satellite.
A. Sezer   +29 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

ASSESSMENT OF SELECTED PHYSICAL AND MECHANICAL PROPERTIES OF CEMENT BONDED BOARD PRODUCED FROM Gliricidia sepium (AGUNMANIYE) [PDF]

open access: yesPro Ligno, 2016
Selected physical and mechanical properties of cement bonded board produced from Gliricidia sepium were assessed. The following board properties were evaluated, water absorption, thickness swelling, water absorption and thickness swelling following ...
John Tosin ALADEJANA   +1 more
doaj  

PAPAN PARTIKEL DARI LIMBAH SERUTAN ROTAN DAN CANGKANG SAWIT

open access: yesJurnal Riset Industri Hasil Hutan, 2013
The research of particle board for interior purpose with the mixed composition of rattan shavings (as core) and oil palm shell (the outer layer) had been done.
Budi Tri Cahyana
doaj   +1 more source

High-density interconnect board design for wafer-level packaging

open access: yesElectronics Letters, 2011
The main advantage of wafer-level packaging is a smaller, thinner and lighter package with minimised electrical length and lower inductance. Presented is a printed circuit board electrical design to assemble a wafer-level package of a wireless radio core. The link impact and challenges are addressed in both time domain and frequency domain.
B. Wu, B. Brown, E. Warner
openaire   +1 more source

Reuse of low-density fibre-boards for insulation use

open access: yes, 2021
Description of the "Reuse of low-density fibre-boards for insulation use" good practice identified in the WoodCircus Project. Page 22 of the Good Practice Catalogue.
Partanen, Asta   +2 more
openaire   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

The Possibility of Replacing Strands in the Core Layer of Oriented Strand Board by Particles from the Stems of Rape (Brassica napus L. var. napus)

open access: yesBioResources, 2016
In this study, reducing the density of oriented strand board (OSB) in the core layer where strands were replaced by rape straw particles was evaluated. The use of rape particles in the core layer did not significantly affect the mechanical properties of ...
Radosław Mirski   +2 more
doaj   +1 more source

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