Results 121 to 130 of about 875,676 (277)

"Who Appoints Them, What Do they Do? Evidence on Outside Directors from Japan" [PDF]

open access: yes
Reformists argue that Japanese firms maintain inefficiently few outside directors, while theory suggests market competition should drive firms toward their firm-specifically optimal board structure (if any). The debate suggests three testable hypotheses.
J. Mark Ramseyer, Yoshiro Miwa
core  

Letter from the Canadian Italian Advocates Organization to Geraldine Ferraro [PDF]

open access: yes, 1984
Letter from the Board of Directors of the Canadian Italian Advocates Organization to Geraldine Ferraro. Letter has handwritten notes.https://ir.lawnet.fordham.edu/vice_presidential_campaign_correspondence_1984_international/1343/thumbnail ...
Canadian Italian Advocates Organization   +1 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Understanding Independence: Board of Directors and CSR. [PDF]

open access: yesFront Psychol, 2020
Calderón R, Piñero R, Redín DM.
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

CGIAR Center Statements on Genetic Resources, Intellectual Property Rights, and Biotechnology [PDF]

open access: yes, 1999
A collection of statements presenting the position of CGIAR centers on genetic resources, intellectual property rights, and biotechnology. Most of these were approved by the CGIAR at its Mid-Term meeting in May 1998, and an additional three at ...
CGIAR Center Directors Committee   +1 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

The Effect of Board Structure on Bidder-Shareholders' Wealth: Further Evidence from the UK Bidding Firms [PDF]

open access: yes
In this study we provide evidence of cross-sectional dependence of bidder-shareholder wealth and target’s board characteristics. More specifically we provide evidence that the percentage of non-executives, the board size, the stock holdings of executives,
Charalambos Th. Constantinou   +1 more
core  

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