Results 141 to 150 of about 26,921 (258)

Biocompatible Sulfobetaine Polymer‐Artemisinin Conjugates Inducing Ferroptosis in Cancer Cells: Synthesis by Mechanochemical Solid‐State Polymerization and Characterization

Macromolecular Rapid Communications, EarlyView.
The amphiphilic copolymer incorporating a hydrophobic chain conjugated with artesunate into a biocompatible sulfobetaine polymer is synthesized by solid‐state copolymerization of sulfobetaine methacrylate and methacrylamide derivative conjugating artesunate.
Naoki Doi, Yukinori Yamauchi, Yasushi Sasai, Ryosuke Nagai, Ayaka Koike, Madoka Ikawa, Toru Yoshimoto, Satoshi Yamada, Masayuki Kuzuya, Shin‐ichi Kondo   +9 more
wiley   +1 more source

Palmitic and oleic acids induce macrophage foam cell formation through C/EBPβ activation. [PDF]

Front Immunol
Wang G, Zhu Y, Liu Y, Huang W, Wei Y, Liu Y, Liu B, Su L.   +7 more
europepmc   +1 more source

LKB1 Loss Sensitizes Lung Tumor Spheres to Mitomet‐Induced Ferroptosis, and These Effects are Enhanced by mTOR Inhibition

Molecular Carcinogenesis, EarlyView.
ABSTRACT Owing to their robust antioxidant defense mechanisms, cancer stem‐like cells (CSCs) maintain a low level of oxidative stress, which is crucial for preserving stemness and pluripotency. Therefore, agents that either directly generate reactive oxygen species (ROS) or inhibit the antioxidant defense systems can selectively induce oxidative cell ...
Xueqing Liang, Ali Nakhi, Peter I. Dosa, Gunda I. Georg, Fekadu Kassie   +4 more
wiley   +1 more source

The innate immune mediator group IIA secreted phospholipase A₂ modulates lipid droplet formation in prostate cancer cells. [PDF]

Front Cell Dev Biol
Andarva M, Elias MG, Sajinovic M, Mann TJ, Zhou JM, Mellick AS, Roberts TL, de Souza P, Scott KF.   +8 more
europepmc   +1 more source

Quantification of 10B and 11B in Biological Samples in Translational Science and Clinical Applications for Boron Neutron Capture Therapy (BNCT)

Medicinal Research Reviews, EarlyView.
ABSTRACT Boron neutron capture therapy (BNCT) is a targeted radiotherapy that exploits the selective accumulation of the 10B isotope within tumors, followed by irradiation with low‐energy neutrons to induce high linear energy transfer particles with short path lengths, resulting in localized tumor cell destruction while sparing surrounding healthy ...
Christoph Selg, Wolfgang A. G. Sauerwein, Evamarie Hey‐Hawkins   +2 more
wiley   +1 more source

Photocontrolled immunotherapy: a BODIPY-caged MSA-2 for spatiotemporal activation of STING with visible light.

New J Chem
Arora K, Lee AE, Chada NC, Schulman JA, Wilson JT.   +4 more
europepmc   +1 more source

Perfluorooctanoic acid (PFOA) induces lipid accumulation, oxidative stress, and reduced neurogenesis in primary human neuronal progenitor cells. [PDF]

Front Toxicol
Marinello WP, Zylka MJ.
europepmc   +1 more source

Branched‐Chain Amino and Keto Acids Reduce Hepatocyte Lipid Droplet Size and Number via Distinct Proteomic Pathways

PROTEOMICS, EarlyView.
ABSTRACT Branched‐chain amino acids (BCAA) and their corresponding keto acids (BCKA) have been associated with changes in hepatic lipid metabolism and the resulting alterations in intracellular triglyceride concentrations. In this study, we utilized a previously established hepatocyte model to investigate the impact of BCAA and BCKA supplementation on ...
Jayasimha R. Daddam, Mounica Sura, Edward Kolodziej, Maria Gojcaj, Zheng Zhou   +4 more
wiley   +1 more source

White light emitting molecular logic gates

Smart Molecules, EarlyView.
White light emitting smart molecules with Boolean logic computing ability are surveyed. Abstract White light emitting (WLE) materials are of considerable interest with commercial and societal applications in video displays and lighting devices. A characteristic property of WLE materials is the luminescence profile spanning from 380 to 700 nm.
Davide Benedetto Tiz, Massimo Catania, David C. Magri   +2 more
wiley   +1 more source

Light and ultrasound activated precision: a novel water-soluble BODIPY-mediated sono-photosensitizer in SPDT for breast cancer treatment. [PDF]

Sci Rep
Can Karanlık C, Türkkol A, Karanlık G, Kolaç UK, Çalışkan ŞG, Bilgin MD, Erdoğmuş A.   +6 more
europepmc   +1 more source