Results 121 to 130 of about 26,921 (258)

Single‐Step Synthesis of Dithieno[3,2‐b:2′,3′‐e]Pyridines and Their Acid‐Dependent Optical and Photosensitising Properties

open access: yesChemistry – A European Journal, EarlyView.
The synthesis of dithieno[3,2‐b:2′,3′‐e]pyridines (DTPs) is herein reported, and their optical properties are studied both experimentally and computationally. Protonation or methylation of the nitrogen atom induced bathochromic shifts in their absorption and emission spectra.
Dominic Taylor   +7 more
wiley   +1 more source

Organelle‐Resolved Tetrazine‐trans‐Cyclooctene Click Chemistry for Cargo Delivery and Release

open access: yesChemistry – A European Journal, EarlyView.
Bioorthogonal click chemistry tools provide a means for specific intracellular conjugation of molecules. In this study, we used reactive tetrazine (Tz) and TCO moieties for labeling of organelles and organelle‐specific delivery and activation of doxorubicin prodrugs.
Oleh Durydivka   +6 more
wiley   +1 more source

Light-driven radical catch-and-release with BODIPY photocages. [PDF]

open access: yesChem Sci
Poryvai A   +5 more
europepmc   +1 more source

Ratiometric pH‐Responsive and Biomimetic Microparticles for Quantitative Monitoring of Phagosomal Acidification

open access: yesChemistry – A European Journal, EarlyView.
A series of hydrosoluble BODIPY pH probes allows building biomimetic pH sensors based on micrometric oil‐in‐water droplets. The ratiometric fluorescence output offers quantitative information on the evolution of pH during phagosome maturation. ABSTRACT We present a modular biomimetic fluorescent sensing platform designed to precisely interrogate the ...
Sophie Michelis   +5 more
wiley   +1 more source

Engineering and Characterization of a Fluorescent Fission Yeast Arp2/3 Complex for Single Molecule Mechanistic Investigations

open access: yesCytoskeleton, EarlyView.
ABSTRACT Arp2/3 complex is a seven‐component protein complex that facilitates the assembly of branched actin filament networks by binding to pre‐existing “mother” actin filaments and initiating the nucleation of new branched “daughter” filaments. Arp2/3 complex must be activated by a nucleation promoting factor such as the WASP/Scar protein family. The
Caitlin A. Anderson   +8 more
wiley   +1 more source

Computational Analysis of Chromophore-Controlled Photoactivation in Monofunctional Platinum(II)-BODIPY Conjugates for Dual Chemo-Photodynamic Therapy. [PDF]

open access: yesChembiochem
BODIPY‐decorated monofunctional Pt(II) complexes were computationally designed as dual chemo‐photodynamic agents. π‐conjugation engineering shifts absorption into the therapeutic window (up to 661 nm) while preserving singlet oxygen generation and DNA platination capability.
Ponte F, Mazzone G.
europepmc   +2 more sources

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