Results 41 to 50 of about 26,921 (258)

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity

Advanced Science, EarlyView.
We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu, Bingwei Wang, Zhijie Su, Xiaoxv Han, Miao He, Yun Zhao, Yujia Hou, Daotong Li, Weiguang Zhang, Lihua Qin, Ke Wang, Yanchun Li, Yi Yan, Siwang Yu, Xiaoshuai Huang, Tairan Yuwen, Jianyuan Luo, Ruimao Zheng   +17 more
wiley   +1 more source

A bodipy based hydroxylamine sensor

Chemical Communications, 2017
With this research we have developed a bodipy based system as the first “turn-on” fluorescence system for the detection hydroxylamine.
Adam C. Sedgwick, Robert S. L. Chapman, Jordan E. Gardiner, Lucy R. Peacock, Gyoungmi Kim, Juyoung Yoon, Steven D. Bull, Tony D. James   +7 more
openaire   +3 more sources

Dataset for the Synthesis of Boron-Dipyrrin Dyes, their fluorescent properties, their interaction with proteins, Triton-X-based surfactants, and micellar clusterization approaches to validation based on fluorescent dyes

Data in Brief, 2022
The data presented here refer to the research article by Aleksei V. Solomonov, Yuriy S. Marfin, Alexander B. Tesler, Dmitry A. Merkushev, Elizaveta A. Bogatyreva, Elena V. Antina, Evgeniy V.
Aleksei V. Solomonov, Yuriy S. Marfin, Alexander B. Tesler, Dmitry A. Merkushev, Elizaveta A. Bogatyreva, Elena V. Antina, Evgeniy V. Rumyantsev, Ulyana Shimanovich   +7 more
doaj   +1 more source

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

Advanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang, Shan Zhang, Junping Bai, Xiaobing Li, Yi Han, Min Ji, Chongyi Jiang, Xiaobei Ge, Tianyu Yu, Yongying Hou, Jun Zhang, Wangting Li, Yiran Song, Jiaying Cai, Yingqun Zhou, Liwei An, Feng Wang   +16 more
wiley   +1 more source

Stepwise Polychlorination of 8-Chloro-BODIPY and Regioselective Functionalization of 2,3,5,6,8-Pentachloro-BODIPY [PDF]

The Journal of Organic Chemistry, 2015
An effective, stepwise methodology for polychlorination of BODIPY using trichloroisocyanuric acid (TCCA) in acetic acid was developed. In this way, selectively substituted di-, tri-, tetra-, and pentachloro-BODIPYs 2-5 were prepared. The pentachloro-BODIPY is shown to undergo regioselective Pd(0)-catalyzed Stille and Suzuki coupling reactions, first at
Ning, Zhao, Sunting, Xuan, Frank R, Fronczek, Kevin M, Smith, M Graça H, Vicente   +4 more
openaire   +2 more sources

Carboxylic Acid Functionalization at the Meso-Position of the Bodipy Core and Its Influence on Photovoltaic Performance

Nanomaterials, 2019
Two bodipy dyes with different carboxylic acids on the meso-position of the bodipy core were prepared and used to sensitize TiO2 photoelectrodes.
Filip Ambroz, Joanna L. Donnelly, Jonathan D. Wilden, Thomas J. Macdonald, Ivan P. Parkin   +4 more
doaj   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Fluorescent BODIPY dyes as ligands for major steroidogenic proteins: in silico evaluation

Журнал Белорусского государственного университета: Химия, 2018
In silico docking simulations of interactions between BODIPY-based fluorescent compounds and mammalian proteins, responsible for steroidogenesis, namely, cytochromes P450: CYP11A1, CYP17A1, CYP19A1, CYP7A1 and STARD1 transport protein, have been ...
Matvey S. Horetski, Yaroslav V. Faletrov, Elena V. Rudaya, Vladimir M. Shkumatov   +3 more
doaj  

4-(4,4-Difluoro-1,3,5,7-tetramethyl-3a-aza-4a-azonia-4-borata-s-indacen-8-yl)benzonitrile

Acta Crystallographica Section E, 2011
The title compound, C20H18BF2N3, contains one C9BN2 (Bodipy) framework and one cyanobenzyl group. The Bodipy framework is essentially planar with a maximum deviation of 0.041 (2) Å.
Yuting Chen, Jianzhuang Jiang
doaj   +1 more source