Results 111 to 120 of about 7,689,116 (321)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Transcriptome analysis of purple and green Apostichopus japonicus reared under different breeding environments

Frontiers in Marine Science
Sea cucumber (Apostichopus japonicus) is one of the cultured species with the highest production value to a single species in China’s marine agricultural industry with high nutritional and medicinal value.
Bohong Liu, Bohong Liu, Bohong Liu, Lili Xing, Lili Xing, Lili Xing, Shilin Liu, Shilin Liu, Shilin Liu, Lina Sun, Lina Sun, Lina Sun, Fang Su, Fang Su, Fang Su, Wei Cui, Wei Cui, Wei Cui, Chunxi Jiang, Chunxi Jiang, Chunxi Jiang   +20 more
doaj   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

B decays to open and hidden charm at Belle

, 2004
The recent Belle collaboration measurements of B decays to open and hidden charm are discussed. Color-suppressed decay branching fractions are measured with an improved accuracy. The branching fractions of the $\bar{B}^0 \to D_s^+ K^-$ and $\bar{B}^0 \to
Drutskoy, A.
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Color Instrument Analysis of Octopus Drying Using Solar Hybrid Dryer [PDF]

BIO Web of Conferences
Octopus drying in Kaur Regency, Bengkulu Province, is done by direct sun drying. It causes low color quality due to UV light. Solar hybrid drying with UV protection is needed to control the color quality of the octopus.
Fatharani Arina, Maissy Faulina, Yuwana Yuwana, Anis Ulfah   +3 more
doaj   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

Analysis and explanation of Sadr al-Mutalahin's view about the truth of visible light [PDF]

حکمت صدرایی
Discussing and examining categories and their types is always considered as one of the most important topics among philosophical issues. Bag category is one of these ten categories. This category includes different types, of which the tangible bag is one
hamidreza khademi, reza hesari
doaj   +1 more source

Satellite Alignment: I. Distribution of Substructures and Their Dependence On Assembly History From N-Body Simulations

, 2014
Observations have shown that the spatial distribution of satellite galaxies is not random, but aligned with the major axes of central galaxies. This alignment is dependent on galaxy properties, such that red satellites are more strongly aligned than blue
Dutton, Aaron, Kang, Xi, Lin, Weipeng, Macciò, Andrea. V., Wang, Yang Ocean, Yu, Yu   +5 more
core   +1 more source