Results 121 to 130 of about 1,671,548 (309)

Nestling condition of a grassland bird is not associated with food availability in restored grasslands

Avian Conservation and Ecology
Grassland bird populations have experienced steep declines in recent decades, necessitating better understanding of factors affecting their reproductive success.
Heather M Kraus, Gregory R Houseman, Mary Liz Jameson, Molly M Reichenborn, W. Alice Boyle, William E Jensen   +5 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Drought-linked resource limitations on the body condition of a large ungulate

Frontiers in Ecology and Evolution
Understanding how indirect effects of climate can interact with density-dependent processes has become increasingly important as variability changes resource availability for wildlife. Both climate and animal density can drive the abundance of vegetation
Casey L. Brown, Ryan M. Nielson, Darren Clark, Ryan Kennedy, Kenneth Loonam, Mary M. Rowland, Michael J. Wisdom   +6 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Influence of Beginning Body Condition Scores on Net Returns From Feeding Cull Cows

The impact of beginning body condition scores on returns from feeding cull cows was investigated in a two year experiment. In each of two culling years, physical performance data and financial data were measured at approximately monthly intervals for ...
Raper, Kellie Curry, Biermacher, Jon T., Amadou, Zakou, Ward, Clement E., Cook, Billy   +4 more
core  

The use of new practices for assessment of body condition score

, 2016
Objective. Two body condition scoring systems were compared to those of interpretation of cow's body condition at a local farm located in Aydin region, Turkey. Materials and methods.
Deniz, Alic Ural, Alic Ural, Deniz
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

The gut microbiota-immune-brain axis in a wild vertebrate: dynamic interactions and health impacts

Frontiers in Microbiology
The gut microbiota-immune-brain axis is a feedback network which influences diverse physiological processes and plays a pivotal role in overall health and wellbeing. Although research in humans and laboratory mice has shed light into the associations and
Hugo Pereira, Joseph I. Hoffman, Joseph I. Hoffman, Joseph I. Hoffman, Joseph I. Hoffman, Joseph I. Hoffman, Oliver Krüger, Oliver Krüger, Gábor Á. Czirják, Tony Rinaud, Meinolf Ottensmann, Kai-Philipp Gladow, Barbara A. Caspers, Barbara A. Caspers, Öncü Maraci, Öncü Maraci, Sylvia Kaiser, Sylvia Kaiser, Nayden Chakarov, Nayden Chakarov   +19 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Automated monitoring of dairy cow body condition, mobility and weight using a single 3D video capture device

, 2018
© 2018 Here we propose a low-cost automated system for the unobtrusive and continuous welfare monitoring of dairy cattle on the farm. We argue that effective and regular monitoring of multiple condition traits is not currently practicable and go on to ...
Hansen, M. F., Smith, L. N., Abdul Jabbar, K., D. Forbes, L.N. Smith, K. Abdul Jabbar, Forbes, D., M.F. Hansen, M.L. Smith, Smith, M. L.   +9 more
core   +2 more sources