Results 141 to 150 of about 1,671,548 (309)

Development of a body condition score in guinea pigs: relationships between body condition and quantitative estimates of body fat

open access: yes, 2012
El propósito del estudio fue contribuir al desarrollo y validación de un índice de condición corporal (ICC) para cuyes del Centro de Investigación IVITA, midiendo su consistencia entre evaluadores y su capacidad de predicción de la acumulación de grasa corporal. Se trabajó con 40 hembras Perú, las cuales fueron sometidas a restricciones variables en la
Ara G., Miguel   +4 more
openaire   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Body Condition Scoring Grid for Zebu cattle (Sahel and Savannah areas)

open access: yes
In tropical countries, and especially in Sub-Saharan Africa (Sahel and Savannah areas), subject to significant quantitative and qualitative variations in the availability of fodder during the year, the dissatisfaction of feed needs is a frequent ...
Vall, Eric
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Depigmented wing patch size is a condition-dependent indicator of viability in male collared flycatchers

open access: yes, 2003
Honesty of sexual advertisement is thought to be the result of signalling costs. Because production costs of depigmented plumage patches are probably very low, their role as honest signals of individual quality has been questioned. Costs of bearing these
Hegyi, Gergely   +4 more
core   +1 more source

Biological Characteristics of the Glacier Lantern Fish Benthosema glaciale (Myctophidae) in Icelandic Waters and the Irminger Sea During Summer

open access: yesEcology and Evolution
Myctophids are one of the most diverse and abundant fish families in the mesopelagic zone, making them a key component in the marine pelagic community.
Charlotte S. Matthews   +3 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Excessive lipid contents in immature oocytes from repeat breeder dairy heifers

open access: yes, 2006
The repeat breeding problem in cattle is widespread among all the heavy dairy breeds in cattle and is being considered as a major problem throughout the world. The aetiology of the repeat breeding is of various origins.
Awasthi, Hitesh
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

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