Results 131 to 140 of about 7,095,749 (253)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

GANHO DE PESO PRÉ E PÓS-DESMAME NO DESEMPENHO REPRODUTIVO DE NOVILHAS DE CORTE AOS QUATORZE MESES DE IDADE

open access: yesCiência Animal Brasileira, 2012
The objective of this experiment was to study the development and reproductive performance of sixty-six Charolais crossbred beef heifers bred at fourteen months of age, classified in four groups according to pre and postweaning average daily weight gain (
Ricardo Zambarda Vaz   +5 more
doaj  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Body Condition Scoring Grid for Zebu cattle (Sahel and Savannah areas)

open access: yes
In tropical countries, and especially in Sub-Saharan Africa (Sahel and Savannah areas), subject to significant quantitative and qualitative variations in the availability of fodder during the year, the dissatisfaction of feed needs is a frequent ...
Vall, Eric
core   +1 more source

Le Plan d'action gouvernemental en matière de condition féminine -- /

open access: yes, 1986
1986 /Le titre varie(rel.
Québec (Province). Secrétariat à la condition féminine
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Body Condition, Metabolic Parameters and Semen Traits in Purebred Spanish Horses. [PDF]

open access: yesAnimals (Basel)
Latorre N   +8 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

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