Results 111 to 120 of about 847,290 (339)
Associations between Traditional Chinese Medicine Body Constitution and Cardiovascular Disease Risk in a White population [PDF]
, 2022 Lihua Shu +10 more
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Relação cintura-quadril e fatores de dieta em adultos
Revista de Saúde PúblicaOBJETIVO: Avaliar as associações entre fatores de dieta e acúmulo de tecido adiposo na região abdominal. MÉTODOS: A partir de um inquérito de base domiciliar realizado no Município do Rio de Janeiro, RJ, em 1995 e 1996, foi investigada a dieta usual em 2.
Paula Aballo Nunes Machado +1 more
doaj
Associations between traditional Chinese medicine body constitution and obesity risk among US adults. [PDF]
Longhua Chin Med, 2023 Zhu X +8 more
europepmc +1 more source
THE CONSTITUTIONAL AND LEGAL STATUS OF THE ROMANIAN COURT OF ACCOUNTS [PDF]
In order to follow the way in which all incomes are charged and the expenses approved by the state budget are used, the Parliament has set up an independent and neutral specialised institution that is meant to exercise a detailed control over the ...
Oana Carolina MOLDOVAN +2 more
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Traditional Chinese medicine body constitution predicts new-onset diabetic albuminuria in patients with type 2 diabetes: Taichung diabetic body constitution prospective cohort study. [PDF]
Medicine (Baltimore), 2022 Lee CH +5 more
europepmc +1 more source