Results 81 to 90 of about 847,290 (339)

Thermal evolution and sintering of chondritic planetesimals III. Modelling the heat conductivity of porous chondrite material

open access: yes, 2014
The construction of models for the internal constitution and the temporal evolution of large planetesimals, the parent bodies of chondrites, requires information on the heat conductivity of the complex mixture of minerals and iron metal found in ...
Akridge   +48 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

A scale for assessing the health of children aged 3–6 years in China: development and validation of the TCM constitution scale (3–6 years)

open access: yesFrontiers in Public Health
BackgroundBased on the Chinese Medicine constitution, this study developed a questionnaire specifically tailored for preschool children.MethodsFirst, a TCM constitution scale for children aged 3–6 years was developed using face-to-face interviews, Delphi
Wenle Li   +8 more
doaj   +1 more source

Empower users of financial information as the IASC Foundation's stakeholders [PDF]

open access: yes
Nicolas Véron comments on the proposal for governance reform (Â?constitution reviewâ??) published in May 2008 by the IASC Foundation, the private-sector body which oversees the setting of International Financial Reporting Standards (IFRS).
Nicolas Véron
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

The original scores of traditional Chinese medicine constitutions are risk and diagnostic factors in middle‐aged and older adults with sarcopenia

open access: yesAging Medicine
Objective Sarcopenia is a geriatric syndrome that occurs with age and is characterized by a gradual decline in muscle mass, power, and functionality.
Xin Nie   +8 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Justifikasi Pelembagaan Peradilan Etik

open access: yesDialogia Iuridica, 2017
This study examines the justification of institutionalize the court of ethic. This type of research is normative juridical. The approach used is a historical, statue, and conceptual approach. The results show that urgency of institutionalization court of
Idul Rishan
doaj   +1 more source

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