Results 71 to 80 of about 376,641 (309)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Wave-body interactions for a surface-piercing body in water of finite depth

open access: yes, 2010
Nonlinear wave-body interactions for a stationary surface-piercing body in water of finite depth with flat and sloping bottoms are simulated in a two-dimensional numerical wave tank, which is constructed mainly based on the spatially averaged Navier ...
林缅, Li Y(李勇), Lin M(林缅)
core   +1 more source

Three-body forces and shell-model binding energies

open access: yesPhysics Letters B, 1975
Abstract Shell-model binding energy data in the sd shell are found to be consistent with a small 3-body force in addition to the usual 1- and 2-body forces. Some credence is given to the analysis by the similarity of the 3-body terms in the binding energies produced by the Kuo and Preedom-Wildenthal interactions and by the expected appearance of very
B.J. Cole, A. Watt, R.R. Whitehead
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Electric potential and ion drag force in highly collisional complex plasma [PDF]

open access: yes, 2008
This PhD thesis is a cumulative dissertation that consists of three papers. The first paper describes the qualitative as well as quantitative nature of the electrostatic potential behind a macroparticle in a drifting collisional plasma and also the ion
Chaudhuri, M., Chaudhuri, Manis
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Investigation of relationship between drag and lift coefficients for a generic car model [PDF]

open access: yes, 2014
The paper presents a study of aerodynamic characteristics of a car, which has the simplified geometric shape, so called Ahmed body. Flow around the body and the influence of its rear slant angle on drag are widely studied by numerous researchers. However,
MASSOUH, Fawaz, DOBREV, Ivan
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Mechanism of nonlinear biodynamic response of the human body exposed to whole-body vibration [PDF]

open access: yes, 2008
When the human body is exposed to mechanical vibration, the resonance frequencies of the frequency response functions, such as apparent mass and transmissibility, decrease with increasing magnitude of excitation. For the past two decades, this biodynamic
Huang, Ya
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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