Results 121 to 130 of about 3,694,866 (341)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Systemic immunity-inflammation index and body mass index: A cross-sectional study

open access: yesPLoS ONE
Background and aimThe Systemic Immunity-inflammation Index (SII) is an emerging metric for assessing an individual's immunological and inflammatory condition. Studies examining the relationship between SII and body mass index (BMI) are limited.
Wei Guo   +5 more
doaj   +2 more sources

Comparison of body composition assessment by DXA and BIA according to the body mass index: A retrospective study on 3655 measures

open access: yesPLoS ONE, 2018
Background and aims Body composition assessment is often used in clinical practice for nutritional evaluation and monitoring. The standard method, dual-energy X-ray absorptiometry (DXA), is hardly feasible in routine clinical practice contrary to ...
N. Achamrah   +8 more
semanticscholar   +1 more source

Effects of Title IX and Sports Participation on Girls' Physical Ability and Weight [PDF]

open access: yes, 2007
Summarizes findings from "Effects of Title IX and Sports Participation on Girls' Physical Ability and Weight," a study of how legislation to increase girls' participation in sports affected physical activity levels, body mass index, and body ...
Deanna Lewis, Robert Kaestner, Xin Xu
core  

Parental stress increases body mass index trajectory in pre-adolescents. [PDF]

open access: yes, 2014
What is already known about this subjectRates of childhood obesity have increased since the mid-1970s. Research into behavioural determinants has focused on physical inactivity and unhealthy diets.
Berhane, K   +7 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Analyses of body composition charts among younger and older Chinese children and adolescents aged 5 to 18 years

open access: yesBMC Public Health, 2012
Background Childhood obesity has become a major public health problem in China. The objective of this study was to examine the effect of age and sex on the relationship between fat-free mass (FFM) and fat mass (FM), fat-free mass index (FFMI) and fat ...
Xiong Kai-Yu   +3 more
doaj   +1 more source

Prognostic potential of body composition indices in detecting risk of musculoskeletal injury in army officer cadet profiles. [PDF]

open access: yes, 2017
OBJECTIVES: High values in most of the body composition indices have been related to musculoskeletal injuries, but limited data exists on the accuracy of these diagnoses when detecting musculoskeletal injuries in military populations.
Bahadori B   +9 more
core   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Home - About - Disclaimer - Privacy