Results 121 to 130 of about 10,342,103 (300)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Infant mortality by maternal prepregnancy body mass index : United States, 2017\u20132018 [PDF]

Objective\u2014This report presents 2017\u20132018 infant mortality rates in the United States by maternal prepregnancy body mass index, and by infant age at death, maternal age, and maternal race and Hispanic origin.Methods\u2014Descriptive tabulations ...

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Body mass index has risen more steeply in tall than in short 3-year olds: serial cross-sectional surveys 1988-2003 [PDF]

, 2007
Objective: To monitor the changing relationship between body mass index ( BMI) and height in young children.Design: Annual cross-sectional surveys using health-visitor-collected routine data 1988 - 2003.Setting: Wirral, England.Participants: Fifty ...
Kitchiner, DJ, Bundred, PE, Buchan, IE, Cole, TJ   +3 more
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Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Lean Mass Index, Not Body Mass Index, is Essentially Associated with Arterial Stiffness in Chinese Adults: A Cross-Sectional Study [PDF]

Xinyi Wang,1,* Ming Yi,1,* Yinghua Zhang,2 Keling Xiao,1 Jin Si,1 Lijie Sun,1 Haoyu Zhang,1 Jinghao Sun,1 Zhaoli Liu,1 Jiaying Lin,1 Yuxin Xie,1 Bingyan Zhang,1 Jing Zhao,3 Xi Chu,3 Jing Li1 1Department of Geriatrics, Xuanwu Hospital ...
Li J, Xie Y, Si J, Zhang H, Chu X, Sun L, Liu Z, Xiao K, Zhang Y, Yi M, Wang X, Lin J, Zhang B, Zhao J, Sun J   +14 more
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Patients’ characteristics divided by Body-Mass-Index.

, 2018
Patients’ characteristics divided by Body-Mass-Index.
Rainer Huegel (5807369), Julian Kofler (5807366), Bernhard Lange-Asschenfeldt (5807372), Markus Richtig (5807354), Günter Schulter (320656), Martin Wolf (740172), Barbara M. Rainer (5807351), Stefan Pilz (279331), Martin R. Grübler (5807357), Erika Richtig (5807375), Akos Heinemann (142582), Georg Richtig (4582933), Christoph Hoeller (268917), Martin Pichler (283174), Ingrid Wolf (119519), Anna Gappmayer (5807360), Thomas Haidn (5807363)   +16 more
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From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Associations between body mass index and severity of psoriasis

, 2017
Mohammadreza Sobhan, Mahmoud Farshchian Psoriasis Research Center, Department of Dermatology, Farshchian Hospital, Hamadan University of Medical Sciences, Hamadan, Iran Objective: Compared with healthy people, overweight and obesity are more ...
Sobhan M, Farshchian M
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Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Mass observation / by Mass Observation.

, 1945
Electronic reproduction. Canberra, A.C.T.
Mass-Observation.
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