Results 111 to 120 of about 3,694,866 (341)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Income and body mass index in Europe [PDF]

The problem of obesity is alarming public health authorities around the world. Therefore, it is important to study its determinants. In this paper we explore the empirical relationship between household income and body mass index (BMI) in nine European ...
Climent Quintana-Domeque, Jaume Garcia Villar   +1 more
core  

Physical activity and cardiovascular mortality risk: possible protective mechanisms? [PDF]

, 2012
INTRODUCTION: The biological mechanisms through which increased physical activity or structured exercise training lowers the risk of recurrent cardiac events are incompletely understood.
Apullan, Clark, Dorn, EMMANUEL STAMATAKIS, Franco, Goldhammer, Hamer, Hamer, Janssen, LEE INGLE, Maria Sarullo, MARK HAMER, Moholdt, Mora, Myers, Myers, Orrell, Sabatine, SEAN CARROLL, Shlipak, Taylor, Taylor, Wannamethee, Whooley, Wisloff, Yu   +25 more
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Associations of Maternal Diabetes and Body Mass Index With Offspring Birth Weight and Prematurity

JAMA pediatrics, 2019
Importance Maternal obesity, pregestational type 1 diabetes, and gestational diabetes have been reported to increase the risks for large birth weight and preterm birth in offspring.
Linghua Kong, I. Nilsson, M. Gissler, C. Lavebratt   +3 more
semanticscholar   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, Volume 20, Issue 6, Page 1643-1660, June 2026.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Correlation Between Body-Shape Index, Body-Roundness Index, Body-Mass Index, and Apnea-Hypopnea Index in Patients with Obstructive Sleep Apnea Syndrome

Journal of Multidisciplinary Healthcare
Mihrican Yeşildağ,1 Zühal Şentürk,1 Taha Tahir Bekci,1 İbrahim Güney,2 Seher Mercan3 1Department of Chest Diseases, S.B University Konya Training and Research Hospital, Konya, Turkey; 2Department of Nephrology, S.
Yeşildağ M, Şentürk Z, Bekci TT, Güney İ, Mercan S   +4 more
doaj  

Maternal body mass index and pregnancy outcomes: a systematic review and metaanalysis.

American Journal of Obstetrics & Gynecology MFM, 2019
OBJECTIVE DATA The purpose of this study was to determine the effect of body mass index category on pregnancy outcomes. STUDY Five databases (Medline, Embase, PubMed, www.clinicaltrials.gov, and Cochrane) were searched from inception until February ...
R. D’Souza, I. Horyn, S. Pavalagantharajah, N. Zaffar, C. Jacob   +4 more
semanticscholar   +1 more source

Time Discounting and the Body Mass Index [PDF]

In many Western countries, the relative weight of people – measured by the Body Mass Index (BMI) – has increased substantially in recent years, leading to an increasing incidence of overweight and related health problems.
Borghans,Lex, Golsteyn,Bart H.H.
core   +1 more source

Worldwide Exposures to Cardiovascular Risk Factors and Associated Health Effects: Current Knowledge and Data Gaps. [PDF]

, 2016
Information on exposure to, and health effects of, cardiovascular disease (CVD) risk factors is needed to develop effective strategies to prevent CVD events and deaths.
Elliott, P, Ezzati, M, Kontis, V, Tzoulaki, I   +3 more
core   +1 more source