Results 101 to 110 of about 3,694,866 (341)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Hypertension, Body Mass Index, and their Associations with Type 2 Diabetes Mellitus in Deli Serdang, North Sumatera [PDF]
, 2018 Background: Diabetes mellitus (DM) is a major public health problem world-wide. Current global estimates indicate that this condition affects 415 million people and is set to escalate to 642 million by the year 2040. Type 2 DM is a metabolic disease that
Aguslina, F. (Fazidah ) +2 more
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
BODY MASS INDEX AND EFFECTS DURING KAYAKING [PDF]
Sport Mont, 2012 Comparison of the results was performed among the sample of 55 male students of second year from the Faculty of Physical Education and Sports at the University of East Sarajevo, School Year 2009/2010, chronologically aged 23 years ±6 months.
Milomir Trivun +3 more
doaj
Alʹmanah Kliničeskoj Mediciny, 2018 Background: Obesity is an important health problem, as its prevalence has reached an epidemic level and continues to increase steadily resulting in higher risk of cardiovascular diseases and metabolic disorders.
I. V. Misnikova +3 more
doaj +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1513-1534, June 2026.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
European Heart Journal, 2019 AIMS Central adiposity is associated with increased cardiovascular disease (CVD) risk, even among people with normal body mass index (BMI). We tested the hypothesis that regional body fat deposits (trunk or leg fat) are associated with altered risk of ...
Guo-Chong Chen +17 more
semanticscholar +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1494-1512, June 2026.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Nutrients, 2019 The associations between visceral adiposity index (VAI), body shape index and diabetes in adults were inconsistent. We assessed the predictive capacity of VAI and body shape index for diabetes by comparing them with body mass index (BMI) and waist ...
Junxiang Wei +4 more
semanticscholar +1 more source
Infant self-regulation and body mass index in early childhood [PDF]
, 2016 BACKGROUND: Poor self-regulation during preschool and early school age years is associated with rapid weight gain. However, the association between self-regulatory capacities in infancy and weight status in early childhood has not been well studied ...
Peacock-Chambers, Elizabeth Marcela
core +1 more source