Results 71 to 80 of about 10,342,103 (300)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Low Body Mass Index for Early Screening of Adolescent Idiopathic Scoliosis: A Comparison Based on Standardized Body Mass Index Classifications

Asian Nursing Research, 2020
Purpose: Scoliosis is a common musculoskeletal problem in adolescents. This study aimed to identify the prevalence of adolescent idiopathic scoliosis (AIS) and its associated factors among Korean adolescents.
Suhee Kim, Ju-Yeon Uhm, Duck-Hee Chae, Yunhee Park   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Body mass index evaluation in hypertensive women [PDF]

Revista Brasileira em Promoção da Saúde, 2003
Hypertension prevalence is approximately three times higher in obese people. This study analyzed the Body Mass Index (BMI) in 200 hypertensive women in follow up treatment in a public hypertension center in the city of Fortaleza-CE, Brazil.
Raimunda Magalhães da Silva, Zélia Maria de Sousa Araújo Santos, Samélia Léa Menezes Becker   +2 more
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Body mass index and serum lipid levels [PDF]

Horizonte Médico, 2016
Objective: To identify the association between the body mass index (BMI) and serum lipid levels in adult people. Material and Methods: Observational, transversal and retrospective study. Non experimental investigation design.
Pedro Javier Navarrete Mejía, Manuel Jesús Loayza Alarico , Juan Carlos Velasco Guerrero, Zoel Aníbal Huatuco Collantes, Ruth Angélica Abregú Meza   +4 more
doaj  

Is body mass index before middle age related to coronary heart disease risk in later life? [PDF]

, 2009
Objective: Although obesity beginning early in life is becoming more common, its implications for coronary heart disease (CHD) risk in later life remain uncertain.
Orfei, L, Osmond, C, Owen, C.G., Cook DG, Whincup, PH, Whincup, P.H., Rudnicka, A.R., Osmond C, A K Wathern, Chou, QA, Eriksson, JG, L Orfei, Eriksson, J.G., C Osmond, Kaye, SJ, D G Cook, Kaye, S.J., Wathern AK, C G Owen, Q-A Chou, Kaye SJ, J G Eriksson, Rudnicka, AR, Wathern, AK, A R Rudnicka, Rudnicka AR, Owen CG, Chou QA, Whincup PH, Eriksson JG, Wathern, A.K., Orfei L, S J Kaye, Cook, D.G., Chou, Q-A., Owen, CG, Cook, DG, P H Whincup, Osmond, C., Orfel, L.   +39 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source