Results 61 to 70 of about 1,284,905 (264)

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

On a Measure of Asymmetry of Convex Bodies

Mathematical Proceedings of the Cambridge Philosophical Society, 1962
In the present note we discuss some properties of a ‘measure of asymmetry’ of convex bodies in n-dimensional Euclidean space. Various measures of asymmetry have been treated in the literature (see, for example, (1), (6); references to most of the relevant results may be found in (4)).
Asplund, E., Grosswald, E., Grünbaum, Branko   +2 more
openaire   +3 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Marmara Hayvancılık Araştırma Enstitüsünde Yetiştirilen Saanen Keçilerin Bazı Tanımlayıcı Özellikleri

Journal of Agricultural Sciences, 2009
Bu çalışma, Marmara Hayvancılık Araştıra Enstitüsü Keçi Yetiştirme Ünitesinde yetiştirilen Saanen keçilerin; bazı üreme özellikleri, oğlaklarda büyüme ve gelişme, ergin yaş canlı ağırlığı ve vücut ölçülerini ortaya koymak amacı ile yürütülmüştür ...
Ayhan Ceyhan, Orhan Karadağ
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Effects of milk fortification with an advanced chelated trace minerals supplement on growth, health, and nutrient digestibility in dairy calves [PDF]

Animal Bioscience
Objective Recent advancements in chelate compound technology offer improved bioavailability of trace minerals, potentially enhancing growth performance and reducing disease incidence.
Hossein Rajaei-Sharifabadi, Hadi Rahmani, Zahra Shokri, Saideh Fakharzadeh, Somayeh Kalanaky, Mohammad Hassan Nazaran, Ahmad Reza Seradj   +6 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Zootechnical Index Analysis of West African Dwarf Rams in Southwestern Nigeria

Agricultura Tropica et Subtropica, 2015
The study was conducted to evaluate the zootechnical index analysis of West African Dwarf (WAD) rams. Twenty body measurements were taken on 100 WAD rams of average ages of 18-24 months.
Popoola Moshood Abiola
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Body morphometric measurements in Murrah crossbred buffaloes (Bubalus bubalis)

Journal of Applied Animal Research, 2018
The morphometry study contributes to the comprehension of the animal conformation. The objective of this research was to study the morphometric measurements of crossbred female Murrah buffaloes, aiming to give subsidies to the study of the relations ...
Breno Araújo de Melo, Isabele de Melo Nascimento, Lays Thayse Alves dos Santos, Luciano Gomes de Lima, Filipe Chagas Teodózio de Araújo, Raisa Rodrigues Santos Rios, Alberto de Gusmão Couto, Angelina Bossi Fraga   +7 more
doaj   +1 more source