Results 81 to 90 of about 822,971 (295)

Relationships Between Personality Features and the Rubber Hand Illusion: An Exploratory Study

Frontiers in Psychology, 2019
The rubber hand illusion paradigm allows investigating human body ownership by inducing an illusion of owning a life-sized fake hand. Despite the wide consensus on the fact that integration of multisensory signals is the main interpretative framework of ...
Dalila Burin, Claudia Pignolo, Francesca Ales, Luciano Giromini, Maria Pyasik, Davide Ghirardello, Alessandro Zennaro, Miriana Angilletta, Laura Castellino, Lorenzo Pia, Lorenzo Pia   +10 more
doaj   +1 more source

Heartfelt embodiment: Changes in body-ownership and self-identification produce distinct changes in interoceptive accuracy [PDF]

, 2017
Interoceptive and exteroceptive information are both essential for the construction and update of self-awareness. Whereas several studies have shown how interoceptive accuracy or cardiac feedback influences body-awareness, no studies have looked at the ...
Ainley, Ainley, Ainley, Allen, Apps, Apps, Aspell, Baier, Bernhardt, Bird, Botvinick, Cardini, Craig, Craig, Critchley, Crucianelli, Devue, Dunn, Edwards, Ehrsson, Ehrsson, Ehrsson, Eshkevari, Fotopoulou, Gu, Herbert, Holle, Jenkinson, Jennings, Kammers, Keizer, Lenggenhager, Limanowski, Lloyd, Longo, Maister, Manos Tsakiris, Maria L. Filippetti, Moseley, Paladino, Pollatos, Ring, Rohde, Rohde, Ronchi, Salomon, Samad, Schandry, Schauder, Schilbach, Sedeño, Sel, Seth, Seth, Simmons, Suzuki, Tajadura-Jiménez, Tajadura-Jiménez, Tajadura-Jiménez, Tsakiris, Tsakiris, Tsakiris, Tsakiris, Tsakiris, Tsakiris, van Stralen   +65 more
core   +3 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

The ambiguous feeling between “mine” and “not-mine” measured by integrated information theory during rubber hand illusion

Scientific Reports, 2022
Human body awareness is adaptive to context changes. The illusory sense of body ownership has been studied since the publication of the rubber hand illusion, where ambiguous body ownership feeling was first defined. Phenomenologically, the ambiguous body
Takayuki Niizato, Yuta Nishiyama, Kotaro Sakamoto, Takumi Kazama, Tatsuya Okabayashi, Taiki Yamaguchi   +5 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

The mark of bodily ownership [PDF]

, 2013
Do bodily sensations include a distinctive experience of the body as of one's own? I am aware that this hand is mine. But is the sense of ownership of my hand manifested to me in a more primitive form than beliefs or judgements?
de Vignemont, Frédérique
core  

The relationship between virtual body ownership and temperature sensitivity. [PDF]

, 2013
In the rubber hand illusion tactile stimulation seen on a rubber hand, that is synchronous with tactile stimulation felt on the hidden real hand, can lead to an illusion of ownership over the rubber hand.
Llobera, Joan, Slater, Mel, Sánchez-Vives, María Victoria   +2 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source