Results 71 to 80 of about 6,162,514 (308)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Elucidation of the genetic determination of body weight and size in Chinese local chicken breeds by large-scale genomic analyses

BMC Genomics
Background Body weight and size are important economic traits in chickens. While many growth-related quantitative trait loci (QTLs) and candidate genes have been identified, further research is needed to confirm and characterize these findings.
Jie Wang, Jie Liu, Qiuxia Lei, Zhihe Liu, Haixia Han, Shuer Zhang, Chao Qi, Wei Liu, Dapeng Li, Fuwei Li, Dingguo Cao, Yan Zhou   +11 more
doaj   +1 more source

An inexpensive and portable microvolumeter for rapid evaluation of biological samples

BioTechniques, 2010
We describe an improved microvolumeter (MVM) for rapidly measuring volumes of small biological samples, including live zooplankton, embryos, and small animals and organs.
John K. Douglass, William T. Wcislo
doaj   +1 more source

Can Self-Esteem Protect Against the Deleterious Consequences of Self-Objectification for Mood and Body Satisfaction in Physically Active Female University Students? [PDF]

, 2011
Using objectification theory (Fredrickson & Roberts, 1997), this study tested the interaction between self-objectification, appearance evaluation, and self-esteem in predicting body satisfaction and mood states.
Bartholomew, Kimberley, Cumming, Jennifer, Ntoumanis, Nikos, Pearce, Gemma, Thøgersen-Ntoumani, Cecilie   +4 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Polynomially filtered exact diagonalization approach to many-body localization

, 2020
Polynomially filtered exact diagonalization method (POLFED) for large sparse matrices is introduced. The algorithm finds an optimal basis of a subspace spanned by eigenvectors with eigenvalues close to a specified energy target by a spectral ...
Lewenstein, Maciej, Sierant, Piotr, Zakrzewski, Jakub   +2 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Finite size errors in quantum many-body simulations of extended systems

, 1998
Further developments are introduced in the theory of finite size errors in quantum many-body simulations of extended systems using periodic boundary conditions. We show that our recently introduced Model Periodic Coulomb interaction [A. J.
A. Baldereschi, A. J. Williamson, A. J. Williamson, A. J. Williamson, A. J. Williamson, B. L. Hammond, B. L. Hammond, B. Tanatar, C. J. Umrigar, C. Kittel, D. Ceperley, D. M. Ceperley, D. M. Ceperley, D. M. Ceperley, D. M. Ceperley, G. E. Engel, G. Rajagopal, G. Rajagopal, G. Rajagopal, H. J. Monkhorst, J. P. Perdew, K. E. Schmidt, L. M. Fraser, L. Mitáš, L. Mitáš, L. Mitáš, L. Mitáš, M. M. Hurley, M. M. Morrell, O. W. Day, P. P. Ewald, P. R. C. Kent, P. R. C. Kent, R. J. Needs, Randolph Q. Hood, S. Fahy, S. W. de Leeuw, S. Öǧüt, W. Knorr, W. L. McMillan, W. M. C. Foulkes, W. von der Linden, X. P. Li, Y. Kwon   +43 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source