Results 91 to 100 of about 2,674,745 (310)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

THE DIFFERENTIATION OF SHEEP BREED BASED ON THE BODY MEASUREMENTS [PDF]

open access: yesJournal of the Indonesian Tropical Animal Agriculture, 2011
This research was carried out to make a difference and to predict genetic distance some sheep that are genetically related to each other based on the body size measurements.
E. Handiwirawan   +3 more
doaj  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Shell Constraints on Evolutionary Body Size–Limb Size Allometry Can Explain Morphological Conservatism in the Turtle Body Plan

open access: yesEcology and Evolution
Turtles are a small clade of vertebrates despite having existed since the Late Triassic. Turtles have a conservative body plan relative to other amniotes, characterized by the presence of a shell and quadrupedality.
Guilherme Hermanson, Serjoscha W. Evers
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Body size changes in passerine birds introduced to New Zealand from the UK

open access: yes, 2013
One feature of global geographic variation in avian body sizes is that they are larger on isolated islands than on continental regions. Therefore, this study aims to assess whether there have been changes in body size following successful establishment ...
Ewen, John   +18 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Direction and magnitude of natural selection on body size differ among age‐classes of seaward‐migrating Pacific salmon

open access: yesEvolutionary Applications, 2020
Due to the mediating role of body size in determining fitness, the “bigger‐is‐better” hypothesis still pervades evolutionary ecology despite evidence that natural selection on phenotypic traits varies in time and space.
Marta E. Ulaski   +2 more
doaj   +1 more source

Can appearance conversations explain differences between gay and heterosexual men's body dissatisfaction? [PDF]

open access: yes, 2014
Men's body dissatisfaction is prevalent and a serious health concern as it is associated with negative outcomes including depression, disordered eating, and anabolic steroid abuse.
Jankowski, Glen   +7 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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