Results 71 to 80 of about 21,157,326 (340)
Identification of Candidate Genes and Functional Pathways Associated with Body Size Traits in Chinese Holstein Cattle Based on GWAS Analysis
Animals, 2023 Body size is one of the most economically important traits of dairy cattle, as it is significantly associated with cow longevity, production, health, fertility, and environmental adaptation.Ismail Mohamed Abdalla, Jiang Hui, Mudasir Nazar, Abdelaziz Adam Idriss Arbab, Tianle Xu, Shaima Mohamed Nasr Abdu, Yongjiang Mao, Zhangping Yang, Xubin Lu +8 moredoaj +1 more sourceThe Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
PLoS Genetics, 2015 Genome-wide association studies (GWAS) have identified more than 100 genetic variants contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI, WHRadjBMI), a measure of body shape.T. Winkler, A. Justice, M. Graff, Llilda Barata, M. Feitosa, Su H. Chu, Jacek Czajkowski, T. Esko, T. Fall, Tuomas O. Kilpeläinen, Ying-Chang Lu, R. Mägi, E. Mihailov, T. Pers, S. Rüeger, A. Teumer, G. Ehret, T. Ferreira, Nancy L. Heard-Costa, J. Karjalainen, V. Lagou, A. Mahajan, M. Neinast, I. Prokopenko, Jeannette Simino, T. Teslovich, R. Jansen, H. Westra, Charles C. White, D. Absher, T. Ahluwalia, Shafqat Ahmad, E. Albrecht, A. C. Alves, Jennifer L. Bragg-Gresham, A. D. de Craen, Joshua C. Bis, A. Bonnefond, G. Boucher, G. Cadby, Yu-Ching Cheng, Charleston W. K. Chiang, Graciela E. Delgado, A. Demirkan, Nicole D Dueker, N. Eklund, G. Eiriksdottir, J. Eriksson, B. Feenstra, K. Fischer, F. Frau, T. Galesloot, F. Geller, A. Goel, M. Gorski, T. Grammer, S. Gustafsson, S. Haitjema, J. Hottenga, J. Huffman, A. Jackson, K. Jacobs, Å. Johansson, M. Kaakinen, M. Kleber, J. Lahti, I. Leach, B. Lehne, You-Fang Liu, K. Lo, M. Lorentzon, J. Luan, P. Madden, M. Mangino, B. Mcknight, C. Medina-Gomez, K. Monda, M. Montasser, Gabriele Müller, M. Müller-Nurasyid, I. Nolte, K. Panoutsopoulou, L. Pascoe, L. Paternoster, N. W. Rayner, F. Renström, Federica Rizzi, L. Rose, Kathy A. Ryan, P. Salo, S. Sanna, H. Scharnagl, Jianxin Shi, A. Smith, L. Southam, A. Stančáková, V. Steinthorsdottir, R. Strawbridge, Yun J. Sung, I. Tachmazidou, Toshiko Tanaka, G. Thorleifsson, S. Trompet, N. Pervjakova, J. Tyrer, L. Vandenput, S. W. van der Laan, N. van der Velde, J. van Setten, J. V. van Vliet-Ostaptchouk, N. Verweij, E. Vlachopoulou, L. Waite, Sophie Wang, Zhao-Ming Wang, Sarah H. Wild, C. Willenborg, James F. Wilson, A. Wong, Jian Yang, L. Yengo, L. Yerges-Armstrong, Lei Yu, Wei-Hua Zhang, Jing-Hua Zhao, E. Andersson, S. J. Bakker, D. Baldassarre, K. Banasik, M. Barcella, C. Barlassina, C. Bellis, P. Benaglio, J. Blangero, M. Blüher, Fabrice Bonnet, L. Bonnycastle, H. Boyd, M. Bruinenberg, A. Buchman, Harry Campbell, Y. Chen, P. Chines, S. Claudi-Boehm, John Cole, F. Collins, E. D. de Geus, L. D. de Groot, M. Dimitriou, J. Duan, S. Enroth, E. Eury, Aliki-Eleni Farmaki, N. Forouhi, N. Friedrich, P. Gejman, B. Gigante, N. Glorioso, Alan S. Go, O. Gottesman, Jürgen Gräßler, H. Grallert, N. Grarup, Yu-Mei Gu, L. Broer, A. Ham, T. Hansen, Tamara B. Harris, C. Hartman, M. Hassinen, Nick Hastie, A. Hattersley, Andrew C. Heath, A. Henders, Dena G. Hernandez, H. Hillege, O. Holmen, K. Hovingh, Jen-Nie Hui, L. Husemoen, N. Hutri-Kähönen, P. Hysi, T. Illig, P. De Jager, S. Jalilzadeh, T. Jørgensen, J. Jukema, M. Juonala, S. Kanoni, Maria Karaleftheri, K. Khaw, L. Kinnunen, S. Kittner, W. Koenig, I. Kolčić, P. Kovács, N. Krarup, W. Kratzer, J. Krüger, D. Kuh, M. Kumari, T. Kyriakou, C. Langenberg, L. Lannfelt, C. Lanzani, Vaneet Lotay, L. Launer, K. Leander, J. Lindström, A. Linneberg, Yan-ping Liu, S. Lobbens, Robert N. Luben, V. Lyssenko, S. Männistö, P. Magnusson, W. McArdle, C. Menni, S. Merger, L. Milani, Grant W. Montgomery, Andrew P. Morris, N. Narisu, M. Nelis, K. Ong, A. Palotie, L. Pérusse, I. Pichler, M. G. Pilia, A. Pouta, Myriam Rheinberger, R. Ribel-Madsen, Marcus Richards, K. Rice, Treva K. Rice, C. Rivolta, V. Salomaa, Alan R. Sanders, Mark A. Sarzynski, S. Scholtens, Robert A. Scott, W. Scott, S. Sebert, Sebanti Sengupta, B. Sennblad, T. Seufferlein, Angela Silveira, P. Slagboom, J. H. Smit, T. Sparsø, K. Stirrups, R. Stolk, H. Stringham, M. Swertz, A. Swift, A. Syvänen, Sian-Tsung Tan, B. Thorand, A. Tönjes, Angelo Tremblay, E. Tsafantakis, P. J. van der Most, U. Völker, M. Vohl, J. Vonk, M. Waldenberger, Ryan W. Walker, R. Wennauer, E. Widén, G. Willemsen, T. Wilsgaard, Alan F. Wright, M. Zillikens, S. V. van Dijk, N. V. van Schoor, F. Asselbergs, P. D. de Bakker, Jacques S. Beckmann, J. Beilby, David A. Bennett, R. N. Bergman, Sven Bergmann, C. Böger, Bernhard O. Boehm, E. Boerwinkle, D. Boomsma, S. Bornstein, E. Bottinger, Claude Bouchard, J. Chambers, S. Chanock, D. Chasman, F. Cucca, D. Cusi, G. Dedoussis, Jeanette Erdmann, J. Eriksson, Denis A. Evans, U. de Faire, M. Farrall, Luigi Ferrucci, Ian Ford, L. Franke, Paul W. Franks, P. Froguel, R. Gansevoort, C. Gieger, H. Grönberg, V. Gudnason, U. Gyllensten, Per Hall, A. Hamsten, P. van der Harst, C. Hayward, M. Heliövaara, C. Hengstenberg, A. Hicks, A. Hingorani, A. Hofman, Frank B. Hu, H. Huikuri, K. Hveem, Alan L. James, J. M. Jordan, A. Jula, M. Kähönen, E. Kajantie, S. Kathiresan, L. Kiemeney, M. Kivimaki, P. Knekt, H. Koistinen, J. Kooner, S. Koskinen, J. Kuusisto, W. Maerz, Nicholas G. Martin, M. Laakso, Timo A. Lakka, T. Lehtimäki, G. Lettre, D. Levinson, L. Lind, M. Lokki, P. Mäntyselkä, M. Melbye, A. Metspalu, B. Mitchell, F. Moll, Jeffrey C. Murray, A. W. Musk, M. S. Nieminen, I. Njølstad, C. Ohlsson, A. Oldehinkel, B. Oostra, L. Palmer, J. Pankow, G. Pasterkamp, N. Pedersen, O. Pedersen, B. Penninx, M. Perola, Annette Peters, O. Polašek, P. Pramstaller, B. Psaty, L. Qi, T. Quertermous, O. Raitakari, T. Rankinen, Rainer Rauramaa, P. Ridker, J. Rioux, F. Rivadeneira, J. Rotter, I. Rudan, H. D. den Ruijter, J. Saltevo, Naveed Sattar, H. Schunkert, P. Schwarz, A. Shuldiner, J. Sinisalo, H. Snieder, T. I. Sørensen, T. Spector, J. Staessen, Bandinelli Stefania, U. Thorsteinsdóttir, M. Stumvoll, J. Tardif, E. Tremoli, Jaakko Tuomilehto, A. Uitterlinden, M. Uusitupa, A. L. Verbeek, S. Vermeulen, J. Viikari, V. Vitart, H. Völzke, P. Vollenweider, G. Waeber, Mark Walker, H. Wallaschofski, N. Wareham, Hugh Watkins, E. Zeggini, A. Chakravarti, D. J. Clegg, L. Cupples, P. Gordon-Larsen, C. Jaquish, D. Rao, G. Abecasis, T. Assimes, I. Barroso, S. Berndt, M. Boehnke, P. Deloukas, C. Fox, L. Groop, David J. Hunter, E. Ingelsson, Robert C. Kaplan, M. McCarthy, K. Mohlke, J. O’Connell, D. Schlessinger, D. Strachan, K. Stefánsson, C. M. van Duijn, J. Hirschhorn, Cecilia M. Lindgren, I. Heid, K. North, I. Borecki, Z. Kutalik, R. Loos +438 moresemanticscholar +1 more sourceIdentifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background
Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods
Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...Hai Pham, Teyl Engstrom, Peter Baade, Natalie Bradford, Sarah Pont, Louise Marquart‐Wilson, Natasha Nassar, Jason D. Pole +7 morewiley +1 more sourceBone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background and Aims
Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran +21 morewiley +1 more sourceEffectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background
Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato +6 morewiley +1 more sourceTP53 copy number expansion is associated with the evolution of increased body size and an enhanced DNA damage response in elephants
bioRxiv, 2015 A major constraint on the evolution of large body sizes in animals is an increased risk of developing cancer. There is no correlation, however, between body size and cancer risk. This lack of correlation is often referred to as ‘Peto’s Paradox’.M. Sulak, Lindsey Fong, Katelyn M. Mika, Sravanthi Chigurupati, L. Yon, N. Mongan, Richard D Emes, Vincent J. Lynch +7 moresemanticscholar +1 more sourceSerum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background
Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima +7 morewiley +1 more source