Results 71 to 80 of about 1,051,443 (344)

07 Intern Assignment Biological Adaptations [PDF]

open access: yes, 2020
WELCOME to WINDOWS on the INQUIRY CLASSROOM! You have landed on a piece of a National Science Foundation Project (DUE 1245730) directed by Professor Chris Bauer, Chemistry Department, University of New Hampshire.
Bauer, Christopher F.
core   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Research on the coordinated control of large permanent magnet direct drive fan and air conditioner based on finite element method

open access: yesEnergy Reports, 2023
In recent years China has committed to energy saving and emission reduction. Chinese Government has proposed a strategic policy of carbon neutrality. In the context of energy shortage, the development of sustainable cities and green buildings is a major ...
Haolin Li   +5 more
doaj   +1 more source

A neuronal relay mediates a nutrient responsive gut/fat body axis regulating energy homeostasis in adult Drosophila [PDF]

open access: yes, 2019
The control of systemic metabolic homeostasis involves complex inter-tissue programs that coordinate energy production, storage, and consumption, to maintain organismal fitness upon environmental challenges.
Bauer, Christin   +8 more
core   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Heatstroke‐like symptoms in a patient with coronavirus disease pneumonia

open access: yesClinical Case Reports, 2020
While there are no clear indications for body temperature control during viral infections such as COVID‐19, if heat stress caused by COVID‐19 leads to organ failure, then proactive body temperature regulation may be an effective treatment option.
Ryo Deguchi   +3 more
doaj   +1 more source

Local temperature-sensitive mechanisms are important mediators of limb tissue hyperemia in the heat-stressed human at rest and during small muscle mass exercise. [PDF]

open access: yes, 2015
Limb tissue and systemic blood flow increases with heat stress, but the underlying mechanisms remain poorly understood. Here, we tested the hypothesis that heat stress-induced increases in limb tissue perfusion are primarily mediated by local temperature-
Ali, L   +7 more
core   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Systemic cardiovascular and carotid baroreflex support of arterial pressure during recovery from passive heat stress in young and older adults

open access: yesPhysiological Reports
We evaluated the systemic cardiovascular and carotid baroreflex support of arterial pressure during recovery from whole‐body, passive heating in young and older adults.
Emily A. Larson   +7 more
doaj   +1 more source

The impacts of environmental warming on Odonata: a review [PDF]

open access: yes, 2008
Climate change brings with it unprecedented rates of increase in environmental temperature, which will have major consequences for the earth's flora and fauna.
Adams J.   +165 more
core   +1 more source

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