Results 81 to 90 of about 11,463,351 (406)

Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment

open access: yesFEBS Letters, EarlyView.
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause   +2 more
wiley   +1 more source

Application value of contrast‐enhanced ultrasound in preoperative localization of microwave ablation for primary hyperparathyroidism

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Background Ultrasonography (US) and 99mTechnetium‐sestamibi scintigraphy (99mTc‐MIBI) are currently first‐line imaging modalities to localize parathyroid adenomas with sensitivities of 80% and 84%, respectively. Therefore, finding other modalities to further improve the diagnostic accuracy for preoperative localization is critically needed ...
Fangyi Liu   +7 more
wiley   +1 more source

Impact of sex, fat distribution and initial body weight on oxytocin’s body weight regulation

open access: yesScientific Reports, 2017
Obesity is considered as a worldwide problem in both males and females. Although many studies have demonstrated the efficiency of oxytocin (Oxt) as an anti-obesity peptide, there is no comparative study of its effect in males and females. This study aims
Yuko Maejima   +7 more
doaj   +1 more source

Cluster sum rules for three-body systems with angular-momentum dependent interactions [PDF]

open access: yesPhys.Rev.C77:024001,2008, 2008
We derive general expressions for non-energy weighted and energy-weighted cluster sum rules for systems of three charged particles. The interferences between pairs of particles are found to play a substantial role. The energy-weighted sum rule is usually determined by the kinetic energy operator, but we demonstrate that it has similar additional ...
arxiv   +1 more source

Testicular growth and comb and wattles development in three Italian chicken genotypes reared under free range conditions [PDF]

open access: yes, 2015
Male chickens belonging to three Italian purebreds \u2013 Ermellinata di Rovigo (ER), Robusta lionata (RL) and Robusta maculata (RM) \u2013 were studied. All the birds were reared under the same rearing conditions (from May until autumn).
DE FASSI NEGRELLI RIZZI, Chiara   +1 more
core   +1 more source

Cross‐sex hormone therapy in transgender persons affects total body weight, body fat and lean body mass: a meta‐analysis

open access: yesAndrologia, 2017
Weight gain and body fat increase the risk of cardiometabolic disease. Cross‐sex hormone therapy in transgender persons leads to changes in body weight and body composition, but it is unclear to what extent.
M. Klaver   +4 more
semanticscholar   +1 more source

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

open access: yesFEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine   +3 more
wiley   +1 more source

Treatment planning with a 2.5 MV photon beam for radiation therapy

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose The shallow depth of maximum dose and higher dose fall‐off gradient of a 2.5 MV beam along the central axis that is available for imaging on linear accelerators is investigated for treatment of shallow tumors and sparing the organs at risk (OARs) beyond it.
Navid Khaledi   +5 more
wiley   +1 more source

Lower-Limb Amputation And Body Weight Changes In Men [PDF]

open access: yes, 2015
Little is known about the relationship between lower-limb amputation (LLA) and subsequent changes in body weight. We conducted a retrospective cohort study using clinical and administrative databases to identify and follow weight changes in 759 males ...
Bouldin, Erin   +1 more
core  

Body fatness or anthropometry for assessment of unhealthy weight status? Comparison between methods in South African children and adolescents [PDF]

open access: yes, 2013
A variety of methods are available for defining undernutrition (thinness/underweight/under-fat) and overnutrition (overweight/obesity/over-fat). The extent to which these definitions agree is unclear.
Armstrong   +6 more
core   +1 more source

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