Results 121 to 130 of about 558,138 (246)
Arquivos Brasileiros de Cardiologia, 2010 FUNDAMENTO: A adoção de medidas de prevenção primária em jovens é de potencial impacto favorável no cenário das doenças cardiovasculares. OBJETIVO: Avaliar a pressão arterial (PA) e variáveis de risco cardiovascular em jovens estratificados pelo ...
Flávia Lopes Fonseca +7 more
doaj +1 more source
Obesogenic Environmental Influences on Young Adults: Evidence From Randomized Dormitory Assignment [PDF]
, 2014 This study utilizes a natural experiment—conditionally random dormitory assignments of first-year US college students—to investigate the influence of obesogenic environmental factors in explaining changes in weight and exercise behavior during the 2009 ...
Eisenberg, Daniel +2 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Square root voting system, optimal threshold and \pi
, 2012 The problem of designing an optimal weighted voting system for the two-tier voting, applicable in the case of the Council of Ministers of the European Union (EU), is investigated.
Slomczynski, Wojciech, Zyczkowski, Karol
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
The Weight of Inequality: Variation with Industrialization and Wealth [PDF]
, 2015 When other economic measurements are scarce or unreliable, height and the body mass index (BMI) are now well accepted measures for cumulative and current net nutrition.
Carson, Scott A.
core
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Journal of Affective Disorders Reports: Background: Previous studies on the relationship between body composition and depressive symptoms have focused on fat or lean mass separately. We aimed to examine the association between the lean-to-fat mass ratio (LFMR) and depressive symptoms in the
Jamee Guerra Valencia +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source