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Research progress on the diagnostic techniques and vaccine development of bovine herpesvirus types 1 [PDF]

Frontiers in Veterinary Science
Bovine herpesvirus type 1 (BoHV-1) constitutes a major etiological agent associated with the onset of bovine respiratory disease in cattle. This virus is widely prevalent across global cattle populations, leading to significant economic losses.
Jianming Zhang, Jian Cao, Liang Cao, Chao Zhang, Liyuan Gong, Xiaohong Kang, Dehong Li, Yang Zhang   +7 more
doaj   +2 more sources

Examination of the lung and lymphoid tissue mRNA transcriptome response in dairy calves following experimental challenge with bovine alphaherpesvirus one (BoHV-1). [PDF]

PLoS One
Bovine alphaherpesvirus one (BoHV-1) is a primary cause of bovine respiratory disease (BRD), and a leading cause of morbidity and mortality in cattle. The transcriptomic responses of key respiratory and immune associated tissues of dairy calves following
O'Donoghue S, Earley B, Johnston D, Finnie MS, Cosby SL, Lemon K, McMenamy MJ, Taylor JF, Kim JW, Morris DW, Waters SM.   +10 more
europepmc   +2 more sources

Glucocorticoid Receptor (GR) and Specificity Protein 1 (Sp1) or Sp3 Transactivate the Bovine Alphaherpesvirus 1 (BoHV-1)-Infected Cell Protein 0 Early Promoter. [PDF]

Viruses
Bovine alphaherpesvirus 1 (BoHV-1) acute infection leads to latently infected sensory neurons in trigeminal ganglia. During lytic infection, the immediate early expression of infected cell protein 0 (bICP0) and bICP4 is regulated by an immediate early ...
Hewawasam S, El-Mayet FS, Jones C.
europepmc   +2 more sources

The Safety and Protective Efficacy Evaluation of an Attenuated M. bovis-BoHV-1 Bivalent Vaccine in Rabbits. [PDF]

Vaccines (Basel), 2023
Bovine respiratory disease (BRD) is a global prevalent multifactorial infection primarily caused by viral and bacterial coinfections. In China, Mycoplasma bovis (M.
Zhang S, Zhang Y, Liu G, Wang C, Ji Y, Chen J, Hu C, Chen X, Guo A, Chen Y.   +9 more
europepmc   +2 more sources

GARP and EARP are required for efficient BoHV-1 replication as identified by a genome wide CRISPR knockout screen. [PDF]

PLoS Pathog, 2023
The advances in gene editing bring unprecedented opportunities in high throughput functional genomics to animal research. Here we describe a genome wide CRISPR knockout library, btCRISPRko.v1, targeting all protein coding genes in the cattle genome ...
Tan WS, Rong E, Dry I, Lillico SG, Law A, Digard P, Whitelaw B, Dalziel RG.   +7 more
europepmc   +2 more sources

Preliminary Evaluation of Lablab purpureus Phytochemicals for Anti-BoHV-1 Activity Using In Vitro and In Silico Approaches. [PDF]

ACS Omega, 2023
Lablab purpureus from the Fabaceae family has been reported to have antiviral properties and used in traditional medical systems like ayurveda and Chinese medicine and has been employed to treat a variety of illnesses including cholera, food poisoning ...
Bhat SS, Pradeep S, Patil SS, Flores-Holguín N, Glossman-Mitnik D, Frau J, Sommano SR, Ali N, Mohany M, Shivamallu C, Prasad SK, Kollur SP.   +11 more
europepmc   +2 more sources

Prevalence and risk factors for Bovine Herpesvirus Type 1 (BoHV-1) infection in Irish beef herds: results from the National Beef Welfare Scheme 2023. [PDF]

Ir Vet J
Infectious bovine rhinotracheitis (IBR), caused by bovine herpesvirus-1 (BoHV-1), is a highly contagious disease with significant economic impacts on the cattle industry.
Brock J, Guelbenzu-Gonzalo M, Lozano JM, Lane EA, Gunn M, Brady S, Thulke HH, Graham DA.   +7 more
europepmc   +2 more sources

Glucocorticoid receptor occupancy of key bovine alphaherpesvirus 1 (BoHV-1) promoters correlates with chromatin remodeling during reactivation from latency. [PDF]

J Virol
Bovine alphaherpesvirus 1 (BoHV-1) continues to be a significant bovine pathogen. Acute infections culminate in lifelong latent infections in sensory neurons of trigeminal ganglia (TG) and the central nervous system.
Ostler JB, Jones C.
europepmc   +2 more sources

Whole blood transcriptome analysis in dairy calves experimentally challenged with bovine herpesvirus 1 (BoHV-1) and comparison to a bovine respiratory syncytial virus (BRSV) challenge. [PDF]

Front Genet, 2023
Bovine herpesvirus 1 (BoHV-1), is associated with several clinical syndromes in cattle, among which bovine respiratory disease (BRD) is of particular significance.
O'Donoghue S, Earley B, Johnston D, McCabe MS, Kim JW, Taylor JF, Duffy C, Lemon K, McMenamy M, Cosby SL, Morris DW, Waters SM.   +11 more
europepmc   +2 more sources

Characterization of Razi Bovine Kidney (RBK) Cell Line as a Sensitive Cell to Bovine Herpesvirus-1 (BoHV-1). [PDF]

Arch Razi Inst, 2023
Viruses are obligate parasites that completely rely on host cells for survival and replication. Razi Bovine Kidney (RBK) cell line was introduced and developed by the Razi Vaccine and Serum Research Institute.
Masoumeh M, Mohsen L, Fattah SN, Ashraf M.   +3 more
europepmc   +2 more sources