Results 81 to 90 of about 1,756,538 (293)

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Priority areas at the frontiers of ecology and energy

Ecosystem Health and Sustainability, 2018
The complexity of economic development and humanitarian crises means that energy science and technology should be involved in actions that address almost every major challenges of ecosystem health and sustainability.
S. K. Chou, Robert Costanza, Philip Earis, Klaus Hubacek, B. Larry Li, Yonglong Lu, Roland Span, Hao Wang, Jianping Wu, Yegang Wu, Jerry J. Yan   +10 more
doaj   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

The voxel-wise analysis of false negative fMRI activation in regions of provoked impaired cerebrovascular reactivity.

PLoS ONE, 2019
Task-evoked Blood-oxygenation-level-dependent (BOLD-fMRI) signal activation is widely used to interrogate eloquence of brain areas. However, data interpretation can be improved, especially in regions with absent BOLD-fMRI signal activation.
Christiaan Hendrik Bas van Niftrik, Marco Piccirelli, Giovanni Muscas, Martina Sebök, Joseph Arnold Fisher, Oliver Bozinov, Christoph Stippich, Antonios Valavanis, Luca Regli, Jorn Fierstra   +9 more
doaj   +1 more source

Feeding preferences of experienced and naïve goats and sheep for the toxic plant Ipomoea carnea subsp. fistulosa

Ciência Rural, 2015
Ipomoea carnea is a toxic plant that grazing goats and cattle may learn to ingest with repeated exposure. The objective of this study was to evaluate the feeding preferences of experienced and non-experienced (naïve) goats and sheep for I.
Carlos Alberto Oliveira Júnior, Gabriela Riet-Correa, Everton Lima, Danilo Maia Leite, James A. Pfister, Daniel Cook, Franklin Riet-Correa   +6 more
doaj   +1 more source

Monocyte LOXHD1 and RHOB Expression Predictive of Progressive Systemic Sclerosis–Associated Interstitial Lung Disease

Arthritis Care &Research, EarlyView.
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla, Robert Lafyatis, Kevin F. Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J. Kass   +13 more
wiley   +1 more source

COPD in Never-Smokers: BOLD Australia Study

International Journal of COPD
Marsha A Ivey,1,2 Sheree M Smith,3,4 Geza Benke,1 Brett G Toelle,5,6 Michael L Hunter,7 Alan L James,8 Graeme P Maguire,9 Richard Wood-Baker,10 David P Johns,11 Guy B Marks,5,12 Michael J Abramson1 1School of Public Health and Preventive Medicine, Monash
Ivey MA, Smith SM, Benke G, Toelle BG, Hunter ML, James AL, Maguire GP, Wood-Baker R, Johns DP, Marks GB, Abramson MJ   +10 more
doaj  

Hip Morphology–Based Osteoarthritis Risk Prediction Models: Development and External Validation Using Individual Participant Data From the World COACH Consortium

Arthritis Care &Research, EarlyView.
Objective This study aims to develop hip morphology‐based radiographic hip osteoarthritis (RHOA) risk prediction models and investigates the added predictive value of hip morphology measurements and the generalizability to different populations. Methods We combined data from nine prospective cohort studies participating in the Worldwide Collaboration ...
Myrthe A. van den Berg, Fleur Boel, Michiel M. A. van Buuren, Noortje S. Riedstra, Jinchi Tang, Harbeer Ahedi, Nigel K. Arden, Sita M. A. Bierma‐Zeinstra, Cindy G. Boer, Flavia M. Cicuttini, Timothy F. Cootes, David T. Felson, Willem Paul Gielis, Joshua Heerey, Graeme Jones, Stefan Kluzek, Nancy E. Lane, Claudia Lindner, Joyce B. J. van Meurs, Andrea Mosler, Amanda E. Nelson, Michael C. Nevitt, Edwin H. Oei, Jos Runhaar, Harrie Weinans, Jesse H. Krijthe, Rintje Agricola   +26 more
wiley   +1 more source

核物理AI研究助手与arXiv向量数据库

He jishu
面对跨学科科学文献的指数级增长与现有检索系统的局限性，本研究基于arXiv平台266万篇论文数据集，创新开发了融合向量语义检索与大型语言模型（Large Language Model，LLM）分析的智能系统。通过构建论文向量数据库实现语义相似性初筛，结合LLM上下文推理优化排序，有效解决了传统关键词搜索的语义鸿沟问题以及LLM的幻觉问题。在核物理领域的应用表明，该系统能精准定位跨学科解决方案，对比特定任务上的关键词检索和向量相似度检索，前10篇文献的查全率从10%跃升到60%，查准率从20%跃升到90%。
庞 龙刚
doaj   +1 more source