Results 141 to 150 of about 11,520 (295)

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

open access: yesExploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi   +5 more
wiley   +1 more source

Mining roof bolting machine safety : a study of the drill boom vertical velocity [PDF]

open access: yes
"This report examines the boom arm vertical speed for roof bolting machines to study a moving boom arm appendage at different speeds during different work scenarios.

core  

Influence of Adhesive Type on Heat Induced Delamination in Tension Loaded Shear Lap Cross‐Laminated Timber Samples Exposed to Radiant Heat Flux

open access: yesFire and Materials, EarlyView.
ABSTRACT Heat induced delamination (HID) is a phenomenon in engineered wood products which may result in the detachment of the bonded timber lamellae before charring propagates to the bond line interphase. This study aims to correlate the thermal degradation of two 1‐c‐polyurethane adhesives at the microscale to the thermo‐hydro‐mechanical behaviour of
A. Čolić   +4 more
wiley   +1 more source

Bolt Fastening by Bolt-Tensioner

open access: yesJournal of the Japan Society for Precision Engineering, 2015
openaire   +2 more sources

Low‐Pressure All‐Solid‐State Lithium–Sulfur Batteries: Challenges and Design Principles

open access: yesInterdisciplinary Materials, EarlyView.
Stack pressure is redefined from an effective laboratory parameter to an external compensation for intrinsic interfacial incompatibility in all‐solid‐state lithium–sulfur batteries (ASSLSBs). This work links low‐pressure degradation to chemo‐mechanical mismatch among volume evolution, interfacial chemistry, charge transport, and mechanical response ...
Xiaowei Liu   +8 more
wiley   +1 more source

What Future Lies Ahead for Circular Business Models Research?

open access: yesStrategic Change, EarlyView.
ABSTRACT The circular economy—wherein waste is designed out, materials are circulated and nature is regenerated—has reached global recognition. From policy to business circles, it is seen as a viable strategy to address multiple societal grand challenges—including climate change and depletion of finite natural resources—and build a more resilient ...
Roberta de Angelis, Kerry Hudson
wiley   +1 more source

Effects of Fertilizer Rates on Growth of <i>Brassica napus</i> L. [PDF]

open access: yesLife (Basel)
Xu Y   +6 more
europepmc   +1 more source

Andrographolide Modulates Fibrogenic and Oxidative Stress Responses in Human Lung Fibroblasts

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pulmonary fibrosis is a progressive lung disorder characterized by fibroblast activation and excessive extracellular matrix deposition. Andrographolide (ANDRO) has been reported to attenuate pulmonary fibrosis, but the underlying molecular mechanisms remain incompletely understood.
Yu‐Hsin Tseng   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy