Results 121 to 130 of about 89,005 (231)

Il ruolo della 'fides' nei fenomeni aggregativi in Roma antica

, 2019
Fides was a fundamental normative parameter in every kind of association: already in societas omnium inter omnes there was a natural law that required compliance with the agreed commitments, but even more important was the principle of fides for the ...
paola lambrini
core  

Tra salvaguardia della libertas e tutela della bona fides: il caso della vendita dell'uomo libero

, 2015
Il contributo si occupa della emptio liberi hominis, analizzata attraverso l’esame delle fonti giuridiche, con il fine di cogliere la logica ad esse sottesa e l’evoluzione del pensiero giurisprudenziale in materia, oscillante tra la salvaguardia della ...
CORBO, CHIARA
core  

Artificial Intelligence‐Assisted Strategies for KEAP1 Modulator Discovery: From Virtual Screening to De Novo Molecular Design

iNew Medicine, EarlyView.
KEAP1 represents a promising target for regulating oxidative‐stress‐associated diseases. AI approaches accelerate KEAP1 inhibitor discovery through structure prediction and virtual screening. Integrated computational and experimental platforms facilitate translational development.
Feilong Zhou, Qiansong Chen, Xing Chen, Baoan Song, Xinhua Liu   +4 more
wiley   +1 more source

The role of rare copy number variants in early‐onset depression

JCPP Advances, EarlyView.
Abstract Background Depression is a highly heterogeneous condition. Depression with an onset in childhood and early adolescence has a worse clinical course, is more heritable, and shows a lower genetic correlation with other depression subtypes, than does later‐onset depression.
Charlotte A. Dennison, Ida Sønderby, Miguel Garcia‐Argibay, Victoria Powell, Amy Shakeshaft, Lucy Riglin, Elliott Rees, Michael O’Donovan, Henrik Larsson, Ole Andreassen, Alexandra Havdahl, Joanna Martin, Anita Thapar   +12 more
wiley   +1 more source

Implications of attention‐deficit/hyperactivity disorder diagnostic timing on mental health service utilisation in young adult females: A population‐based record linkage cohort study

JCPP Advances, EarlyView.
Abstract Background Sex differences in the frequency and timing of attention‐deficit/hyperactivity disorder (ADHD) diagnosis exist. While there are multiple known individual and wider consequences for young females with delayed or undiagnosed ADHD, little is known about mental health service utilisation (HSU) impacts.
Estelle Alderson, Nicholas Bowden, Laurie McLay, Ben Beaglehole, Philip J. Schluter   +4 more
wiley   +1 more source

Differences in associations between attention‐deficit hyperactivity disorder symptoms and physical activity across childhood and adolescence and among males and females in a representative UK birth cohort

JCPP Advances, EarlyView.
Abstract Background Children and adolescents with attention‐deficit hyperactivity disorder (ADHD) exhibit higher physical activity (PA) levels than peers without ADHD. It remains unclear how this association evolves across developmental stages and differs between sexes.
Amandine Sénéquier, Stamatina Iliodromiti, Jessica Agnew‐Blais   +2 more
wiley   +1 more source

Mass Spectrometry‐Based Extracellular Vesicle Proteomics for Biomarker Discovery

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicle (EV) proteomics has emerged as a powerful platform for decoding intercellular communication and advancing biomarker discovery across human diseases. EVs carry proteins that reflect their cells of origin, offering a minimally invasive window into physiological and pathological processes.
Ya‐Juan Liu, Juan Peng, Chao Kang
wiley   +1 more source

Fides

Placa litografiada y troquelada. El término latino Fides, término técnico–jurídico muy utilizado en el derecho romano, significa fe. La compañía aseguradora certifica y rubrica su credibilidad.
Fides
core   +1 more source

Artificial Intelligence for Identifying Tumor‐Reactive CD8+ T Cells: Biological Principles, Computational Advances, and Future Directions

Med Research, EarlyView.
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang, Yingying Sun, Yan Zhang, Yifen Shi, Zhiwen Shi   +4 more
wiley   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source