Results 181 to 190 of about 24,376 (300)

Newspaper Media Framing of the Immigrant Workforce in the Context of Florida's 2023 Immigration Law. [PDF]

Ann Anthropol Pract
Luque JS, Kline NS, Matthew OO, Denis-Luque MF.   +3 more
europepmc   +1 more source

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

Brain Pathology, EarlyView.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga, Eva Fernández‐Muñoz, Jorge M. Charco, Enric Vidal, Diego Herrero‐Martínez, Josu Galarza‐Ahumada, Cristina Sampedro‐Torres‐Quevedo, Samanta Giler, Mariví Geijo, Gloria González‐Aseguinolaza, Hasier Eraña, Joaquín Castilla   +11 more
wiley   +1 more source

Techno-Environmental Assessment of Biodiesel Production from Acid Oil via One-Step and Two-Step Esterification. [PDF]

ACS Omega
Myint NN, Jaruensri K, Sakulshah N, Thanapimmetha A, Saisriyoot M, Chiarasumran N, Wang HD, Srinophakun P.   +7 more
europepmc   +1 more source

Not the Last Word: Surprise Medical Bills are Hardly Charitable. [PDF]

Clin Orthop Relat Res, 2020
Bernstein J.
europepmc   +1 more source

Molecular basis for a pore block of Tentonin 3 expressed in HEK293 cells by a conopeptide, NMB‐1

British Journal of Pharmacology, EarlyView.
Background and Purpose Tentonin 3 (TTN3/TMEM150C) is a mechanosensitive ion channel that plays critical roles in mechanotransduction processes. TTN3 forms a tetramer with a predicted rectangular shape and a central pore. A conotoxin ρ‐TIA and its synthetic analog, noxious mechanosensation blocker 1 (NMB‐1), were initially developed to inhibit slowly ...
Sujin Lim, Junhyuk Woo, Sungmin Pak, Joonho Paik, Gyu‐Sang Hong, Ji Hun Wi, Sanghee Lee, Cristina Fenollar‐Ferrer, Kyungreem Han, Young Kee Shin, Uhtaek Oh   +10 more
wiley   +1 more source

Vesicular glutamate transporter VGLUT2 expression emerges in substantia nigra dopamine neurons in mouse models of parkinsonism in the absence of neurodegeneration

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Subsets of midbrain dopamine (DA) neurons express the vesicular glutamate transporter VGLUT2 and can release the excitatory neurotransmitter glutamate. VGLUT2+ DA neurons of the substantia nigra pars compacta (SNc) were shown to be more resistant to neurodegeneration in animal models of Parkinson's disease (PD ...
Sivakumar Srinivasan, Christian Pifl, Thomas Steinkellner   +2 more
wiley   +1 more source

Motivation Relationships with Physical Activity and Resistance Training Engagement, and Health and Fitness of Law Enforcement Officers. [PDF]

Healthcare (Basel)
Sanchez KJ, Beitzel MM, Dawes JJ, Orr RM, Dulla JM, Lockie RG.   +5 more
europepmc   +1 more source

Improving obesity management: Insights from the ACTION Switzerland survey of people with obesity, physicians and dietitians

Clinical Obesity, Volume 15, Issue 2, April 2025.
PwO, people with obesity. Summary ACTION Switzerland (NCT05232786) examined obesity‐related perceptions, attitudes, behaviours and potential barriers to treatment among people with obesity (PwO) and healthcare professionals (HCPs). In March/April 2022, adult PwO (body mass index ≥30 kg/m2, per self‐reported height/weight) and physicians/certified ...
Dominique Durrer, Patrick Pasi, Ralph Peterli, Doris Fischer‐Taeschler, Gabriela Fontana, Gionata Cavadini, Philipp A. Gerber   +6 more
wiley   +1 more source

Identification and Phylogenetic Characterisation of Novel Adeno‐Associated Virus Capsids in Non‐Human Primate Tissues

Cell Proliferation, EarlyView.
AAV's widespread application is currently confronting critical challenges. This study established a systematic framework of ‘natural discovery–evolutionary analysis–functional optimization’, providing a new paradigm for the development of next‐generation AAV vectors with clinical‐grade tissue specificity, low immunogenicity, and cross‐species ...
Liyu Zhu, Kai Xu, Yali Ding, Kailun Liu, Jing Liu, Zongren Hou, Rui Niu, Ning Yang, Hualing Qin, Baoyang Hu, Ying Zhang, Wei Li   +11 more
wiley   +1 more source

The Responsibility to Advocate-and to Advocate Responsibly. [PDF]

Milbank Q, 2019
Pollack HA.
europepmc   +1 more source