Results 31 to 40 of about 199,493 (265)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Steel and concrete bond stress: a contribution to the study of APULOT tests using concrete with rubber addition

open access: yesRevista IBRACON de Estruturas e Materiais, 2014
The bond stress between steel and concrete is the essential condition to the good behaviour of reinforced concrete structures. To preview the use of concrete with waste incorporation for structural aims, the verification of its quality control is ...
A. E. P. G. De Avila Jacintho   +3 more
doaj  

Bond Stress Behavior of a Steel Reinforcing Bar Embedded in Geopolymer Concrete Incorporating Natural and Recycled Aggregates

open access: yesInfrastructures
The rise in greenhouse gases, particularly carbon dioxide (CO2) emissions, in the atmosphere is one of the major causes of global warming and climate change.
Qasim Shaukat Khan   +4 more
doaj   +1 more source

Experimental Study on the Bonding Behavior between Ribbed Steel Bars and Ultra-High-Performance Concrete [PDF]

open access: yes预应力技术
To evaluate the bonding behavior between ribbed steel bars and ultra-high-performance concrete (UHPC), several pull-out samples were experimentally investigated and presented.
Xinzhi Duan
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Effect of accelerated time-dependent corrosion on reinforcement concrete and ultra- high performance concrete: Finite element method analysis

open access: yesVietnam Journal of Science, Technology and Engineering
In this study, finite element analysis using Ansys software was employed to evaluate the bond stress-slip behaviour of corroded steel bars in reinforced concrete structures.
Nguyen Thanh Hung   +3 more
doaj   +1 more source

Bond behavior between concrete and steel rebars for stressed elements

open access: yesAin Shams Engineering Journal, 2021
Earlier research efforts related to concrete-to-steel rebar bond behavior predominantly focused on common parameters such as concrete strength, rebar diameter, bonded length and concrete cover, disregarding the actual/real state of concrete that ...
Yousef R. Alharbi   +3 more
doaj   +1 more source

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