Results 51 to 60 of about 199,493 (265)

Steel and concrete bond stress: a contribution to the study of APULOT tests using concrete with rubber addition

Revista IBRACON de Estruturas e Materiais
The bond stress between steel and concrete is the essential condition to the good behaviour of reinforced concrete structures. To preview the use of concrete with waste incorporation for structural aims, the verification of its quality control is ...
A. E. P. G. De Avila Jacintho, L. L. Pimentel, M. P. Barbosa, P. S. P. Fontanini   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Bonding Strength of Alumina Joint Bonded under the Alternating Stress

Journal of the Ceramic Society of Japan, 1993
Two alumina cylinders of commercial purity, 10mm high and 10mm in diameter were bonded together using an aluminum film. In addition to the normal bonding process, bonding under alternating bonding pressure was performed, and the effect of the alternating applied stress on the bonding strength of the joint was investigated based upon the statistical ...
SASAKI, Kazunori, MOTOIE, Katsuhiko, KAWASAKI, Tadashi   +2 more
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Uniaxial Bond Stress-Slip Relationship of Reinforcing Bars in Concrete

Advances in Materials Science and Engineering, 2012
This paper documents a study carried out on the estimation of the bond stress-slip relationship for reinforced concrete members under axial tension loading.
Sungnam Hong, Sun-Kyu Park
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Comportamento de emenda por traspasse de barras comprimidas em contato e separadas

Revista IBRACON de Estruturas e Materiais
Neste trabalho é resumido um estudo experimental sobre o comportamento de emendas por traspasse de barras comprimidas em pilares de concreto armado, com o objetivo de investigar a influência da distância entre as barras emendadas sobre o comportamento da
C. B. Quintana, G. B. Guimarães, L. D. Shehata   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source