Results 71 to 80 of about 199,493 (265)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Modeling Uniaxial Bond Stress-Slip Behavior of Reinforcing Bars Embedded in Concrete with Different Strengths. [PDF]

Materials (Basel), 2021
Tang CW.
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

EVALUATION OF ASPHALT PAVEMENT LAYER BONDING STRESS

Journal of Civil Engineering and Management, 2015
This study is to evaluate the bonding shear stress between asphalt pavement layered structures with emulsion and cutback asphalt as tack coat materials. A simple direct shear test device is set up for testing the shear force of the pavement composite interface. The test results show that the shear force decreases with an increase in temperature. It had
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

KEKUATAN LEKAT BETON DAN BAJA TULANGAN AKIBAT PEMANASAN

Civil Engineering Dimension, 2003
The combination of concrete and steel form economical and efficient composite material by means of the created cooperation through bond stress on the interface of both materials.
Ellen Kumaat
doaj  

Bond-Slip Constitutive Relationship between Steel Rebar and Concrete Synthesized from Solid Waste Coal Gasification Slag

Buildings
Bond performance served as a crucial foundation for the collaboration between concrete and steel rebar. This study investigated the bond performance between coal gasification slag (CGS) concrete, an environmentally friendly construction material, and ...
Huawei Li, Haozhe Chen, Qingke Nie, Junchao Yu, Liang Zhang, Qingjun Wang   +5 more
doaj   +1 more source

Application of artificial neural networks and multiple linear regression on local bond stress equation of UHPC and reinforcing steel bars. [PDF]

Sci Rep, 2021
Amini Pishro A, Zhang S, Huang D, Xiong F, Li W, Yang Q.   +5 more
europepmc   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source