Results 41 to 50 of about 100,227 (266)

Optimizing Sustainability of Concrete Structures Using Tire-Derived Aggregates: A Performance Improvement Study

CivilEng, 2023
Tire-derived aggregate concrete (TDAC), or rubberized concrete, is gaining ground as an eco-friendly option in civil engineering. By substituting traditional coarse aggregates with recycled rubber tires, TDAC offers a greener choice with excellent energy
Zeinab A. Younis, Maryam Nazari
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Evaluation of Microleakage in Fissure Sealants following Contamination with Artificial Saliva at Different Curing Times with or without using bonding agent

Journal of Islamic Dental Association of Iran, 2018
Background and Aim: One of the important factors in microleakage of fissure sealants is saliva contamination. Researchers believe that applying bonding agents can reduce the microleakage.
Bahman Seraj, Saeedeh Mokhtari, Sara Ghadimi, Fatemeh Ghanaat, Hossein Bagheri   +4 more
doaj  

Development trend analysis of grinding tool technology based on patent perspective -Take porous abrasive tools as example

Jin'gangshi yu moliao moju gongcheng
ObjectivesPorous abrasive tools have the function of chip holding and heat dissipation, which can improve the mechanical grinding process. Patent are the main means of intellectual property protection, and important patent information can reflect the ...
Libing CHEN, Qi SU
doaj   +1 more source

A new adhesive technique for internal fixation in midfacial surgery

BioMedical Engineering OnLine, 2008
Background The current surgical therapy of midfacial fractures involves internal fixation in which bone fragments are fixed in their anatomical positions with osteosynthesis plates and corresponding screws until bone healing is complete.
Riediger Dieter, Stoll Christian, Wirtz Dieter, Tinschert Joachim, Marx Rudolf, Endres Kira, Smeets Ralf   +6 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Effect of Saliva Contamination on Microleakage of a Fissure Selant with or without Bonding Agent

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2012
Introduction: Contamination of etched enamel to saliva before placement of sealant prevents the appropriate bonding and results in microleakage. Using bondings is effective for decreasing the microleakage.
A Abarghooyi, M Mousavi Nasab, M Kabudan, Z Bahrololumi, AA Soleimani   +4 more
doaj  

Optical Bonding Agents for Severe Environments [PDF]

Applied Optics, 1970
Test results and applications of elastors (General Electric RTV 665, Dow Corning (DC) XR-63-488, DC 93-500, DC 182, and DC 184) considered for use as optical bonding agents in aerospace environments are presented.
openaire   +2 more sources

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source