Results 41 to 50 of about 100,439 (264)

The Bond Agent System and Applications

open access: yes, 2000
In this paper we present the basic design philosophy of the Bond agent system, the multi-plane agent model and the component-based architecture implementing the model. We discuss several applications of Bond agents: resource discovery, an adaptive video service, a workflow management system, a system of agents for remote monitoring of web servers, and ...
Boloni, Ladislau   +4 more
openaire   +2 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Effect of Precuring and Postcuring of Total-Etch and Self-Etch Bonding Agents on the Microleakage of Fissure Sealants

open access: yesFrontiers in Dentistry, 2020
Objectives: Considering the importance of timesaving in pediatric dentistry, if the efficacy is achieved along with shorter working time and less technical sensitivity, the behavior management of young patients can be anticipated.
Bahman Seraj   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Development trend analysis of grinding tool technology based on patent perspective -Take porous abrasive tools as example

open access: yesJin'gangshi yu moliao moju gongcheng
ObjectivesPorous abrasive tools have the function of chip holding and heat dissipation, which can improve the mechanical grinding process. Patent are the main means of intellectual property protection, and important patent information can reflect the ...
Libing CHEN, Qi SU
doaj   +3 more sources

Tensile Bond Strength of Self Adhesive Resin Cement After Various Surface Treatment of Enamel [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: In self adhesive resin cements adhesion is achieved to dental surface without surface pre-treatment, and requires only single step application.
Sahil Sekhri   +2 more
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

The use of image analysis for the interaction of 1,3,5-trisubstituted isocyanurates with oxidizer and different binders in composite materials [PDF]

open access: yesHemijska Industrija, 2006
Composite propellants are non-homogenous propellants and comprise primarily crystalline oxidizer and metal fuels uniformly suspended in a resin binder.
Dostanić Jasmina   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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