Results 51 to 60 of about 100,439 (264)

Antibacterial Activity of the Vancomycin and Cefotaxime-Incorporated Total Etch Adhesive System – An In Vitro Study

open access: yesJournal of Pharmacy and Bioallied Sciences
BackgroundMarginal failure at the resin dentin interface promotes biofilm formation, which further leads to secondary caries and hypersensitivity. This likelihood also increases if residual bacteria are present following cavity preparation.
Rangareddy M. S   +4 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Evaluation of Microleakage in Fissure Sealants following Contamination with Artificial Saliva at Different Curing Times with or without using bonding agent

open access: yesJournal of Islamic Dental Association of Iran, 2018
Background and Aim: One of the important factors in microleakage of fissure sealants is saliva contamination. Researchers believe that applying bonding agents can reduce the microleakage.
Bahman Seraj   +4 more
doaj  

Optimizing Sustainability of Concrete Structures Using Tire-Derived Aggregates: A Performance Improvement Study

open access: yesCivilEng, 2023
Tire-derived aggregate concrete (TDAC), or rubberized concrete, is gaining ground as an eco-friendly option in civil engineering. By substituting traditional coarse aggregates with recycled rubber tires, TDAC offers a greener choice with excellent energy
Zeinab A. Younis, Maryam Nazari
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Effect of Saliva Contamination on Microleakage of a Fissure Selant with or without Bonding Agent

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2012
Introduction: Contamination of etched enamel to saliva before placement of sealant prevents the appropriate bonding and results in microleakage. Using bondings is effective for decreasing the microleakage.
A Abarghooyi   +4 more
doaj  

A new adhesive technique for internal fixation in midfacial surgery

open access: yesBioMedical Engineering OnLine, 2008
Background The current surgical therapy of midfacial fractures involves internal fixation in which bone fragments are fixed in their anatomical positions with osteosynthesis plates and corresponding screws until bone healing is complete.
Riediger Dieter   +6 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Composite resin repairs: What is the most effective protocol?

open access: yesBrazilian Dental Science, 2017
Objective: The objective of this study was to evaluate the combination effect of surface treatments and bonding agents on bond strength of repairs on aged composite resin. Materials and Methods: One hundred twenty microhybrid composite units (Filtek Z250)
Alessandra Pereira Andrade   +2 more
doaj   +1 more source

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