Results 11 to 20 of about 3,575,357 (310)
Cell, 2002 We have identified a novel zinc finger-containing transcription factor, called Osterix (Osx), that is specifically expressed in all developing bones. In Osx null mice, no bone formation occurs.
K. Nakashima +6 more
semanticscholar +1 more source
Bioactive Materials, 2021 Bone-tissue defects affect millions of people worldwide. Despite being common treatment approaches, autologous and allogeneic bone grafting have not achieved the ideal therapeutic effect.
GuanYin Zhu +9 more
semanticscholar +1 more source
Subchondral bone microenvironment in osteoarthritis and pain
Bone Research, 2021 Osteoarthritis comprises several joint disorders characterized by articular cartilage degeneration and persistent pain, causing disability and economic burden.
Yan Hu +4 more
semanticscholar +1 more source
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
Nature Medicine, 2012 Tumor-derived exosomes are emerging mediators of tumorigenesis. We explored the function of melanoma-derived exosomes in the formation of primary tumors and metastases in mice and human subjects.
H. Peinado +23 more
semanticscholar +1 more source
FDA-Approved Bone Grafts and Bone Graft Substitute Devices in Bone Regeneration
Materials Science and Engineering C: Materials for Biological Applications, 2021 To induce bone regeneration there is a complex cascade of growth factors. Growth factors such as recombinant BMP-2, BMP-7, and PDGF are FDA-approved therapies in bone regeneration.
C. Gillman, A. Jayasuriya
semanticscholar +1 more source
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
Nature, 2010 The cellular constituents forming the haematopoietic stem cell (HSC) niche in the bone marrow are unclear, with studies implicating osteoblasts, endothelial and perivascular cells.
S. Méndez-Ferrer +9 more
semanticscholar +1 more source
Habis Manis Sepah Jadi Uang: Pemanfaatan Ampas Tebu Menjadi Boneka Arang Aktif
Dinamisia, 2021 In the eyes of the people in Arasoe Village, bagasse does not have a high benefit, it is only used as an embankment in a water channel or allowed to pile up. The bagasse pile is sometimes burned to reduce the quantity in the environment. However, burning
Sumiati +5 more
doaj +1 more source
Mechanisms of bone development and repair
Nature reviews. Molecular cell biology, 2020 Bone development occurs through a series of synchronous events that result in the formation of the body scaffold. The repair potential of bone and its surrounding microenvironment — including inflammatory, endothelial and Schwann cells — persists ...
Ankit Salhotra +3 more
semanticscholar +1 more source
Bone grafts and biomaterials substitutes for bone defect repair: A review
Bioactive Materials, 2017 Bone grafts have been predominated used to treat bone defects, delayed union or non-union, and spinal fusion in orthopaedic clinically for a period of time, despite the emergency of synthetic bone graft substitutes.
Wenhao Wang, K. Yeung
semanticscholar +1 more source
Wnt/β-catenin signaling components and mechanisms in bone formation, homeostasis, and disease
Bone ResearchWnts are secreted, lipid-modified proteins that bind to different receptors on the cell surface to activate canonical or non-canonical Wnt signaling pathways, which control various biological processes throughout embryonic development and adult life ...
Lifang Hu +3 more
semanticscholar +1 more source