Results 41 to 50 of about 2,697,359 (292)

The benefits of data mining

open access: yeseLife, 2017
Careful analysis of a database populated by physicians and patients sheds new light on the side effects of drugs.
Audrey Bone, Keith Houck
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Review Essay: What Is the Contribution of Discourse Linguistics to Foucaultian Discourse Analysis?

open access: yesForum: Qualitative Social Research, 2010
Foucauldian discourse analysis has developed as a field in the social sciences and has established itself as a methodological approach in qualitative social research.
Rainer Diaz-Bone
doaj  

Bone formation on calcium phosphate bone substitute materials [PDF]

open access: yes, 2010
A large number of bone substitute materials are available; for which some authors claim osteoconductivity and some osteoinductivity. In order to rank these materials an in vivo analysis was carried out.
Samizadeh, S.
core  

Peak bone mass after exposure to antenatal betamethasone and prematurity: Follow-up of a randomized controlled trial

open access: yes, 2006
Small birth size is associated with reduced adult bone mass. We determined if antenatal betamethasone exposure, birth weight, or prematurity affects peak bone mass in 174 adults. Antenatal betamethasone exposure did not.
Thomas J Beck   +13 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

THE EVOLUTION OF BONE [PDF]

open access: yesEvolution, 1987
Vertebrates are practically unique among the Metazoa in their possession of a skeleton made from calcium phosphate rather than calcium carbonate. Interpretation of the origin of a phosphatic skeleton in early vertebrates has previously centered primarily on systemic requirements for phosphate and/or calcium storage or excretion.
John A, Ruben, Albert A, Bennett
openaire   +2 more sources

Practical Elaborations. About the Development of Foucauldian Discourse Analysis in Germany

open access: yesForum: Qualitative Social Research, 2006
The German researcher of discourse Jürgen LINK and his team in the Bochumer (later Dortmunder) "discourse workshop" are among the pioneers in the field of discourse analytic research in the social sciences.
Rainer Diaz-Bone
doaj  

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