Results 51 to 60 of about 3,955,837 (304)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Practical Elaborations. About the Development of Foucauldian Discourse Analysis in Germany
Forum: Qualitative Social Research, 2006 The German researcher of discourse Jürgen LINK and his team in the Bochumer (later Dortmunder) "discourse workshop" are among the pioneers in the field of discourse analytic research in the social sciences.
Rainer Diaz-Bone
doaj
Arthroplasty, 2020 Background Pain management after total knee arthroplasty (TKA) is important as acute postoperative pain can affect patient’s ability to walk and participate in rehabilitation required for good functional outcome.
S. K. S. Marya +5 more
doaj +1 more source
Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass. [PDF]
, 2012 Aging reduces the number of mesenchymal stem cells (MSCs) that can differentiate into osteoblasts in the bone marrow, which leads to impairment of osteogenesis.
Guan, Min +11 more
core +1 more source
Strontium potently inhibits mineralisation in bone-forming primary rat osteoblast cultures and reduces numbers of osteoclasts in mouse marrow cultures [PDF]
, 2014 The basic mechanisms by which strontium ranelate acts on bone are still unclear. We show that an important action of strontium salts is to block calcification in cultures of osteoblasts, the bone-forming cells.
A Barbara +44 more
core +3 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Review Essay: Does Qualitative Network Analysis Exist?
Forum: Qualitative Social Research, 2007 Social network analysis was formed and established in the 1970s as a way of analyzing systems of social relations. In this review the theoretical-methodological standpoint of social network analysis ("structural analysis") is introduced and the different
Rainer Diaz-Bone
doaj
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
The Performativity of Qualitative Social Research
Forum: Qualitative Social Research, 2011 Within the last two decades qualitative social research has established itself in most, if not all, of the social sciences. But this emergence has proceeded very differently in institutional and in socio-cognitive aspects.
Rainer Diaz-Bone
doaj
Indonesian Journal of Learning Education and Counseling, 2019 The ROAR learning model is learning that gives students the broadest opportunity to develop concepts, pre-existing ideas become new concepts. The concept is built through direct observation because during learning the teacher presents examples of reality
Emmi Azis +5 more
doaj +1 more source