Results 71 to 80 of about 3,955,837 (304)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Critical Discourse Analysis. The Elaboration of a Problem Oriented Discourse Analytic Approach After Foucault

Forum: Qualitative Social Research, 2006
: The German discourse researcher Siegfried JÄGER from Duisburg is the first to have published a German-language book about the methodology of discourse analysis after FOUCAULT.
Rainer Diaz-Bone
doaj  

High-Impact Mechanical Loading Increases Bone Material Strength in Postmenopausal Women-A 3-Month Intervention Study. [PDF]

, 2018
Bone adapts to loading in several ways, including redistributing bone mass and altered geometry and microarchitecture. Because of previous methodological limitations, it is not known how the bone material strength is affected by mechanical loading in ...
Hellgren, Martin, Kazakia, Galateia J, Lorentzon, Mattias, Nilsson, Martin, Pasco, Courtney, Sundh, Daniel, Yilmaz, Melis, Zoulakis, Michail   +7 more
core   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Karyotype abnormalities and their clinical significance in a group of chronic myeloid leukemia patients treated with hematopoietic stem cell transplantation

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Following hematopoietic stem cell transplantation (HSCT), karyotyping is a valuable tool for monitoring engraftment and disease status.
Luize Otero, Maria Helena Ornellas, Alexandre Mello de Azevedo, Rita de Cássia Tavares, Virgínia Pires, Eliana Abdelhay, Luis Fernando Bouzas, Teresa de Souza Fernandez   +7 more
doaj   +1 more source

Correlation Between Low Bone Density and Disease Activity in Patients with Ulcerative Colitis [PDF]

, 2015
BACKGROUND Different clinical and epidemiological studies using dual-energy X-ray absorptiometry have shown an increased prevalence of low bone mineral density in patients with inflammatory bowel diseases.
Aghaei, M., Amiriani, T., Besharat, M., Besharat, S., Faghani, M., Joshaghani, H., Mirkarimi, H.S., Pourramezan, Z., Roshandel, G.   +8 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Exosomes as Emerging Therapeutic Strategies in Primary Osteoporosis: A Narrative Review [Corrigendum]

Drug Design, Development and Therapy
Chen G, Li H, Chen R, Chen G. Drug Des Devel Ther. 2025;19:9099—9115. The authors have advised that they overlooked including an Acknowledgment section on page 9113 of the published paper. The acknowledgment statement should read as follows.
Chen G, Li H, Chen R, Chen G
doaj  

Milieu Models and Milieu Instruments in Market Research

Forum: Qualitative Social Research, 2004
In the case of social milieu research, the practical, non-scientific context of market research can create problems for practical social research. Some of these problems are examined in this paper.
Rainer Diaz-Bone
doaj  

Understanding Ohio Soils [PDF]

PDF pages ...
Bone, Samuel, Morse, H. H.
core