Results 81 to 90 of about 2,426,310 (311)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Exosomes as Emerging Therapeutic Strategies in Primary Osteoporosis: A Narrative Review [Corrigendum]

open access: yesDrug Design, Development and Therapy
Chen G, Li H, Chen R, Chen G. Drug Des Devel Ther. 2025;19:9099—9115. The authors have advised that they overlooked including an Acknowledgment section on page 9113 of the published paper. The acknowledgment statement should read as follows.
Chen G, Li H, Chen R, Chen G
doaj  

Milieu Models and Milieu Instruments in Market Research

open access: yesForum: Qualitative Social Research, 2004
In the case of social milieu research, the practical, non-scientific context of market research can create problems for practical social research. Some of these problems are examined in this paper.
Rainer Diaz-Bone
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Collective Review: Developments in the Field of the Foucauldian Discourse Analysis

open access: yesForum: Qualitative Social Research, 2003
This article reviews some new international releases in the field of discourse analysis in the tradition of Michel FOUCAULT. This kind of Foucauldian discourse analysis is related to other forms in the wider interdisciplinary field of discourse analysis.
Rainer Diaz-Bone
doaj  

Embedding eSkills in Initial Teacher Training

open access: yesTeaching in Lifelong Learning: A Journal to Inform and Improve Practice, 2011
The decision to become a teacher is a noble and rewarding choice but it presents individuals with many challenges. Trainee teachers are often overwhelmed by the amount of knowledge they are expected to acquire in order to be an effective teacher ...
Szpytma, Elaine, Bone, Catherine
doaj   +1 more source

The characterisation of fossil bone [PDF]

open access: yes, 1993
This research presents a multi-disciplinary approach to the analysis of ancient bones, in which many different chemical and physical analytical techniques were applied to a relatively small sample of human and animal bones from different depositional ...
Turner-Walker, Gordon Howard   +1 more
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Review Essay: Situational Analysis—Strauss Meets Foucault?

open access: yesForum: Qualitative Social Research, 2012
With the (German translation) of the volume "Situational Analysis" by Adele CLARKE, a new approach to the development of Grounded Theory Methodology (GTM) is presented. CLARKE radicalizes the methodological standpoint of classical pragmatism.
Rainer Diaz-Bone
doaj  

Ética profesional. Análisis desde el quehacer psicojurídico ecuatoriano

open access: yesRevista Oficial del Poder Judicial
En la actualidad, donde la palabra corrupción está ligada comúnmente a la falta de valores éticos y morales, así como al deseo desbordado del ser humano de tener por encima de ser, muchos abrigamos la esperanza del despertar, a la luz de la ética y la ...
Mónica Alexandra Francis Bone
doaj   +1 more source

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