Results 91 to 100 of about 2,697,359 (292)

SIPAKAINGE FIT: GAMIFIKASI BERNUANSA LOKAL UNTUK MEMBANGUN REMAJA BUGIS YANG TANGGUH DAN BERGIZI MELALUI PENDIDIKAN JASMANI SEBAGAI UPAYA PREVENTIF STUNTING

Riyadhoh: Jurnal Pendidikan Olahraga
Stunting masih menjadi masalah kesehatan masyarakat utama di Indonesia, khususnya di Kabupaten Bone yang mencatat prevalensi 32,9% pada tahun 2024, jauh di atas rata-rata nasional.
Maria Herlinda Dos Santos, Asmah Amir, Hezron Alhim Dos Santos, Rita Erawati, Nusrsyafikah -, Aryanindya Yuni Alfyanti   +5 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Effects of anti-resorptive agents on trabecular bone score (TBS) in older women.

, 2013
We evaluated the longitudinal effects of anti-resorptive agents (534 treated women vs. 1,150 untreated) on lumbar spine bone mineral density (BMD) and trabecular bone score (TBS). TBS was responsive to treatment in women over age 50.
Aubry-Rozier, B., Hans, D., Leslie, W.D., Manitoba Bone Density, Program, Krieg, M.A.   +4 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Bone and Bones: Fundamentals of Bone Biology.

Archives of Pediatrics & Adolescent Medicine, 1947
  +7 more sources

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Close to the bone: investigations into bone tissue mineralisation and mechanobiology of osteoporosis

, 2012
Osteoporosis is a metabolic skeletal disease characterized by low bone mass, depleted micro-architecture and reduced strength. The public health costs of osteoporosis relate almost entirely to the fractures that are the clinical manifestation of the ...
Brennan, Meadhbh
core   +1 more source

Uncoupling of bone formation with resorption in osteoarthritis subchondral bone in postmenopausal women: associated with osteocyte dysfunction?

, 2010
link_to_subscribed_fulltextThe International Conference on Osteoporosis and Bone Research, Shenzhen, China, 28-31 October 2010. In Bone, 2010, v. 47 suppl. 3, p.
Chunyi Wen, Chun Hoi Yan, Phil Salmon, Xu Cao, Lu, WW, KwongYuen Chiu, Yan, CH, Cao, X, William Weijia Lu, Chiu, K, Wen, C, Ting Wang, Wang, T, Salmon, P   +13 more
core   +1 more source