Results 111 to 120 of about 2,426,310 (311)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

SIPAKAINGE FIT: GAMIFIKASI BERNUANSA LOKAL UNTUK MEMBANGUN REMAJA BUGIS YANG TANGGUH DAN BERGIZI MELALUI PENDIDIKAN JASMANI SEBAGAI UPAYA PREVENTIF STUNTING

Riyadhoh: Jurnal Pendidikan Olahraga
Stunting masih menjadi masalah kesehatan masyarakat utama di Indonesia, khususnya di Kabupaten Bone yang mencatat prevalensi 32,9% pada tahun 2024, jauh di atas rata-rata nasional.
Maria Herlinda Dos Santos, Asmah Amir, Hezron Alhim Dos Santos, Rita Erawati, Nusrsyafikah -, Aryanindya Yuni Alfyanti   +5 more
doaj   +1 more source

THE TRANSPLANTATION OF BONE [PDF]

BMJ, 1918
During recent years the science of bone transplantation has been occupying the attention of orthopedic surgeons to a steadily increasing degree. While the earlier operations were pure experiments attended by success or failure, depending on whether the surgeon chanced to employ the principles that are essential to success, the mass of evidence now at ...
openaire   +4 more sources

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Close to the bone: investigations into bone tissue mineralisation and mechanobiology of osteoporosis

, 2012
Osteoporosis is a metabolic skeletal disease characterized by low bone mass, depleted micro-architecture and reduced strength. The public health costs of osteoporosis relate almost entirely to the fractures that are the clinical manifestation of the ...
Brennan, Meadhbh
core  

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Misdiagnosis of osteoporosis based on a single bone mineral density measurement

, 2010
A bone mineral density (BMD) T-score at or below −2.5 is considered to be osteoporotic However, the uncertainty of BMD measurement can result in a false positive or a false negative diagnosis.
Nguyen, Nguyen D., Frost, Steven A. (R12308), Nguyen, Tuan V., Eisman, John A.   +3 more
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Injectable Cell-based Tissue Engineered Bone Formulations

, 2010
PhDCurrent golden standard therapy for bone repair and regeneration involves the use of auto grafts. Nevertheless, there are many drawbacks associated with auto grafts including donor site morbidity, requirement for an invasive surgery, post-operative
Ahmadi, Raheleh
core