Results 101 to 110 of about 7,204,437 (249)
Objective: In cases of precocious puberty, the determination of bone age (BA) is usually performed by clinicians using the Greulich-Pyle (GP) atlas, and there can be significant variation between assessors.
Murat Hüseyin Yiğit +3 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Navigating Pubertal Goldilocks: The Optimal Pace for Hierarchical Brain Organization
Adolescence is a timed process with an onset, tempo, and duration. Nevertheless, the temporal dimension, especially the pace of maturation, remains an insufficiently studied aspect of developmental progression.
Hanna Szakács +7 more
doaj +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Biomechanical Properties of Bone and Biomechanics of Age - Related Fractures - Review
From a biomechanical viewpoint, fractures are due to a structural failure of the bone. This failure occurs when the forces applied to the bone exceed its load – bearing capacity.
Rezzan Günaydın +1 more
core
BONE STRENGTH OF DIFFERENT PIGS GENETIC TYPES [PDF]
The aim of this study was to evaluate the bone strength in different genetic types of pigs. Nowadays, in swine production it is rather common to obtain pigs with weak bones, especially on the hind legs.
Griggio, Michele
core
Purpose This study aimed to evaluate the short-term benefits of GnRHa therapy, with a specific focus on the first year of treatment, in girls diagnosed with idiopathic central precocious puberty (ICPP) after age 8, providing essential evidence to inform ...
Ming-ming Ni +6 more
doaj +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
A freshwater diet-derived C-14 reservoir effect at the Stone Age sites in the Iron Gates gorge [PDF]
Human bones from single inhumation burials and artifacts made from terrestrial mammal (ungulate) bone found in direct association with the skeletons were obtained from the Stone Age site of Schela Cladovei situated just below the iron Gates Gorge of the ...
Bonsall, C. +5 more
core +1 more source
BackgroundTurner syndrome (TS), a chromosomal disorder affecting females, is commonly associated with short stature due to haploinsufficiency of the SHOX gene.
Yu-Ting Chang +4 more
doaj +1 more source

