Results 111 to 120 of about 1,019,186 (310)

Navigating Pubertal Goldilocks: The Optimal Pace for Hierarchical Brain Organization

Advanced Science
Adolescence is a timed process with an onset, tempo, and duration. Nevertheless, the temporal dimension, especially the pace of maturation, remains an insufficiently studied aspect of developmental progression.
Hanna Szakács, Murat Can Mutlu, Giulio Balestrieri, Ferenc Gombos, Jochen Braun, Morten L. Kringelbach, Gustavo Deco, Ilona Kovács   +7 more
doaj   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Efficacy of first-year GnRHa therapy in girls with idiopathic central precocious puberty diagnosed after age 8: a retrospective study

Gynecological Endocrinology
Purpose This study aimed to evaluate the short-term benefits of GnRHa therapy, with a specific focus on the first year of treatment, in girls diagnosed with idiopathic central precocious puberty (ICPP) after age 8, providing essential evidence to inform ...
Ming-ming Ni, Shu-ting Yang, Jie-yu Sun, Wen-wen Wu, Man Li, Wei Gu, Xing Ji   +6 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Growth hormone therapy and chromosomal mosaicism in turner syndrome: 25 years of growth outcomes in Taiwan

Frontiers in Endocrinology
BackgroundTurner syndrome (TS), a chromosomal disorder affecting females, is commonly associated with short stature due to haploinsufficiency of the SHOX gene.
Yu-Ting Chang, Yu-Ting Chang, Ying-Hua Huang, Ying-Hua Huang, Fu-Sung Lo   +4 more
doaj   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Shell formation and bone strength in laying hens [PDF]

, 2013
In Sweden almost 3.8% of all eggs are ruined due to cracked eggshells as shell quality declines with age during the laying period. This is a concern for food safety as well as an economical problem.
Wistedt, Anna
core  

MAVIDOS maternal vitamin D osteoporosis study: study protocol for a randomized controlled trial. The MAVIDOS Study Group

, 2012
: MAVIDOS is a randomised, double-blind, placebo-controlled trial (ISRCTN82927713, registered 2008 Apr 11), funded by Arthritis Research UK, MRC, Bupa Foundation and NIHR.BACKGROUND:Osteoporosis is a major public health problem as a result of associated ...
Gandhi Saurabh V, Javaid, M.K., Schoenmakers, I., Nicholas Bishop, Fraser, R, Schoenmakers, I, Gandhi, Saurabh V., Ann Prentice, Nicholas C Harvey, Prentice, A., Prentice, A, Cooper Cyrus, Cyrus Cooper, Schoenmakers, Inez, Harvey, NC, Bishop, N., Inez Schoenmakers, Harvey, N.C., Kennedy, S., Schoenmakers Inez, Kassim Javaid, Prentice, Ann, Robert Fraser, Kennedy, Stephen, Prentice Ann, Papageorghiou, A.T., Harvey, Nicholas C., Fraser Robert, Fraser, Robert, Stephen Kennedy, Cooper, Cyrus, Papageorghiou, Aris T., Gandhi, SV, Javaid Kassim, Fraser, R., Kennedy, S, Papageorghiou Aris T, Saurabh V Gandhi, Bishop Nicholas, Javaid, Kassim, Gandhi, S.V., Javaid, K., Bishop, N, Kennedy Stephen, Cooper, C., Javaid, K, Aris T Papageorghiou, Harvey Nicholas C, Cooper, C, Papageorghiou, AT, Bishop, Nicholas   +50 more
core   +1 more source

Comparison of Methods used for Final Height Prediction in Patients with Central Precocious Puberty

JCRPE
Objective: Various methods may be used to estimate target height in patients diagnosed with precocious puberty. These methods include the Bayley-Pinneau (BP) and Roche-Wainer-Thissen (RWT) methods.
Nisa Nur Turan, Aşan Önder Çamaş, Burçin Çiçek, Merve Nur Hepokur, Hamdi Cihan Emeksiz   +4 more
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source