Results 111 to 120 of about 1,856,861 (309)

Skeletal Age Assessment According to The Greulich and Pyle Atlas in Different Skeletal Malocclusions

Turkish Journal of Orthodontics, 2012
Aim:To compare the skeletal age (SA) of the patients with and without different sagittal skeletal malocclusions of the jaws and to compare differences between males and females.Subjects and Methods:The sample comprised 120 patients (mean age 12.00±1.10 ...
Mevlüt Çelikoğlu, Doğan Kılkış, Mehmet Bayram, Metin Nur   +3 more
doaj   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Determining ‘Age at Death’ for Forensic Purposes using Human Bone by a Laboratory-based Analytical Method [PDF]

, 2013
Determination of age-at-death (AAD) is an important and frequent requirement in contemporary forensic science and in the reconstruction of past populations and societies from their remains.
A. Williams, Baccino, Bertelsen, Castillo, Chan, Csapo, Fanton, Feik, Feik, Fernandez-Castillo, Fleischman, Franklin, G. Christodoulou, Griffin, Helfman, Jankauskas, Kanchan-Talreja, Liu, Martin-De Las Heras, Nielsen-March, Obert, Ohtani, Oliver, P. Zioupos, R. Giles, Rho, Ritz, Sakuma, Scheuer, Scheuer, Schmitt, Stein, Thomas, Thompson, Waite, Watanabe, Zioupos, Zioupos, Zioupos, Zioupos, Zioupos   +40 more
core   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

MANDIBULAR SHAPE IN MYOSTATIN-DEFICIENT MICE: A GEOMETRIC MORPHOMETRIC ANALYSIS [PDF]

, 2012
The relationship between muscle function and mandibular morphology is unclear. Manipulating the size or function of muscle and then observing the effect on adjacent bone is one way to explore this relationship.
Johnston, Fayth
core  

Higher fracture prevalence and smaller bone size in patients with hEDS/HSD-a prospective cohort study

, 2020
Increased fracture risk in patients with Ehlers-Danlos syndromes has been reported, but the reasons for it are incompletely understood. We aimed to investigate possible determinants of this increased risk and found that hEDS/HSD patients present with a ...
Banica, Thiberiu, Calders, Patrick, Coussens, Marie, De Wandele, Inge, Goemaere, Stefan, Lapauw, Bruno, Malfait, Fransiska, Rombaut, Lies, Verroken, Charlotte, Zmierczak, Hans-Georg   +9 more
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Growth Assessment and Nutritional Status in Children with Congenital Adrenal Hyperplasia—A Cross-Sectional Study from a Vietnamese Tertiary Pediatric Center

Diagnostics
Background/Objectives: Children with congenital adrenal hyperplasia (CAH) face significant risks of impaired growth and metabolic disturbances despite standard glucocorticoid therapy.
Thi Thuy Hong Nguyen, Khanh Minh Le, Thi Anh Thuong Tran, Khanh Ngoc Nguyen, Thi Bich Ngoc Can, Phuong Thao Bui, Dat Tien Tran, Chi Dung Vu   +7 more
doaj   +1 more source