Results 141 to 150 of about 11,392,113 (401)

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Determining ‘Age at Death’ for Forensic Purposes using Human Bone by a Laboratory-based Analytical Method [PDF]

, 2013
Determination of age-at-death (AAD) is an important and frequent requirement in contemporary forensic science and in the reconstruction of past populations and societies from their remains.
A. Williams, Baccino, Bertelsen, Castillo, Chan, Csapo, Fanton, Feik, Feik, Fernandez-Castillo, Fleischman, Franklin, G. Christodoulou, Griffin, Helfman, Jankauskas, Kanchan-Talreja, Liu, Martin-De Las Heras, Nielsen-March, Obert, Ohtani, Oliver, P. Zioupos, R. Giles, Rho, Ritz, Sakuma, Scheuer, Scheuer, Schmitt, Stein, Thomas, Thompson, Waite, Watanabe, Zioupos, Zioupos, Zioupos, Zioupos, Zioupos   +40 more
core   +1 more source

Aging mechanisms in bone

BoneKEy Reports, 2012
Advancing age and loss of bone mass and strength are closely linked. Elevated osteoblast and osteocyte apoptosis and decreased osteoblast number characterize the age-related skeletal changes in humans and rodents. Similar to other tissues, oxidative stress increases in bone with age.
openaire   +3 more sources

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Navigating Pubertal Goldilocks: The Optimal Pace for Hierarchical Brain Organization

Advanced Science
Adolescence is a timed process with an onset, tempo, and duration. Nevertheless, the temporal dimension, especially the pace of maturation, remains an insufficiently studied aspect of developmental progression.
Hanna Szakács, Murat Can Mutlu, Giulio Balestrieri, Ferenc Gombos, Jochen Braun, Morten L. Kringelbach, Gustavo Deco, Ilona Kovács   +7 more
doaj   +1 more source

Heritability of Changes in Bone Size and Bone Mass With Age in Premenopausal White Sisters [PDF]

, 2006
Siu L. Hui, Daniel L. Koller, Tatiana Foroud, Michael J. Econs, C. Conrad Johnston, Munro Peacock   +5 more
openalex   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Efficacy of first-year GnRHa therapy in girls with idiopathic central precocious puberty diagnosed after age 8: a retrospective study

Gynecological Endocrinology
Purpose This study aimed to evaluate the short-term benefits of GnRHa therapy, with a specific focus on the first year of treatment, in girls diagnosed with idiopathic central precocious puberty (ICPP) after age 8, providing essential evidence to inform ...
Ming-ming Ni, Shu-ting Yang, Jie-yu Sun, Wen-wen Wu, Man Li, Wei Gu, Xing Ji   +6 more
doaj   +1 more source

Characterisation and textural analysis of Middle Bronze Age Transdanubian inlaid wares of the Encrusted Pottery Culture, Hungary: a preliminary study

, 2008
Inlaid ceramics belonging to the Encrusted Pottery Culture and dated to the Middle Bronze Age (2000–1500 BC) are highly distinctive vessels with complex decorative motifs found in large numbers in the Transdanubia region of Hungary.
Kiss, V., Roberts, S., Sofaer, J.
core   +1 more source

Automated Assessment of Bone Age Using Deep Learning and Gaussian Process Regression

Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2018
Bone age is an essential measure of skeletal maturity in children with growth disorders. It is typically assessed by a trained physician using radiographs of the hand and a reference model.
T. Steenkiste, Joeri Ruyssinck, Olivier Janssens, Baptist Vandersmissen, F. Vandecasteele, P. Devolder, E. Achten, S. V. Hoecke, D. Deschrijver, T. Dhaene   +9 more
semanticscholar   +1 more source