Results 51 to 60 of about 11,147,694 (408)

Determinants of Muscle and Bone Aging [PDF]

Journal of Cellular Physiology, 2015
Loss of bone and muscle with advancing age represent a huge threat to loss of independence in later life. Osteoporosis represents a major public health problem through its association with fragility fractures, primarily of the hip, spine and distal forearm.
Curtis, Elizabeth M., Litwic, A., Cooper, C., Dennison, E.   +3 more
openaire   +5 more sources

Phospho1 deficiency transiently modifies bone architecture yet produces consistent modification in osteocyte differentiation and vascular porosity with ageing [PDF]

, 2015
PHOSPHO1 is one of principal proteins involved in initiating bone matrix mineralisation. Recent studies have found that Phospho1 KO mice (Phospho1-R74X) display multiple skeletal abnormalities with spontaneous fractures, bowed long bones, osteomalacia ...
Carriero, A, Chang, Y M, Farquharson, C, Houston, D A, Javaheri, B, Kazeruni, B N, Millan, J L, Oldknow, K J, Pitsillides, A A, Salmon, P, Shefelbine, S, Staines, K A   +11 more
core   +3 more sources

Ages and Bone Ageing in Diabetes Mellitus [PDF]

Journal of Diabetes & Metabolism, 2013
يرتبط داء السكري من النوع 1 والنوع 2 بانخفاض في جودة العظام مما يؤدي إلى زيادة في الكسور منخفضة الإجهاد، وهي حالة تسمى اعتلال العظام السكري. وتشير مجموعة متزايدة من الأدلة بقوة إلى أن إحدى الآليات المرضية الرئيسية لاعتلال العظام السكري هي التراكم المفرط للمنتجات النهائية المتقدمة للسكري (AGEs) على الكولاجين من مصفوفة العظام خارج الخلية.
McCarthy, Antonio Desmond, Molinuevo, María Silvina, Cortizo, Ana María   +2 more
openaire   +5 more sources

Dynamics of Bone Trap-5b Level in Patients with Bone Metastases of Renal Cell Cancer at Combined Treatment [PDF]

, 2017
The objective of this study was to determine the sensitivity of tartrate-resistant acid phosphatase (Bone TRAP-5b) for early detection of bone metastases (BM) and to investigate the efficacy of bisphosphonates (BF) (zolendronic acid-ZA) in prevention of ...
Boichuk, S. (Serhiy), Diedkov, A. (Anatoliy), Kostiuk, V. (Viktor), Ostafiychuk, V. (Vasyliy)   +3 more
core   +2 more sources

Pubertal timing in children with Silver Russell syndrome compared to those born small for gestational age

Frontiers in Endocrinology, 2022
ContextData on pubertal timing in Silver Russell syndrome (SRS) are limited.Design and methodsRetrospective observational study including twenty-three SRS patients [11p15 loss of methylation, (11p15 LOM, n=10) and maternal uniparental disomy of ...
Giuseppa Patti, Giuseppa Patti, Federica Malerba, Maria Grazia Calevo, Maurizio Schiavone, Marco Scaglione, Emilio Casalini, Silvia Russo, Daniela Fava, Daniela Fava, Marta Bassi, Flavia Napoli, Anna Elsa Maria Allegri, Giuseppe D’Annunzio, Roberto Gastaldi, Mohamad Maghnie, Mohamad Maghnie, Natascia Di Iorgi, Natascia Di Iorgi   +18 more
doaj   +1 more source

Assessment of trabecular bone score (TBS) in overweight/obese men: effect of metabolic and anthropometric factors [PDF]

, 2016
The "trabecular bone score" (TBS) indirectly explores bone quality, independently of bone mineral density (BMD). We investigated the effects of anthropometric and metabolic parameters on TBS in 87 overweight/obese men. We assessed BMD and TBS by DXA, and
Carnevale, Vincenzo, COSTANTINI, DANIELA, GNESSI, Lucio, LENZI, Andrea, LUBRANO, Carla, Migliaccio, Silvia, MORANO, Susanna, Nieddu, Luciano, Romagnoli, Elisabetta   +8 more
core   +1 more source

Bone age assessment with various machine learning techniques: A systematic literature review and meta-analysis

PLoS ONE, 2019
BACKGROUND The assessment of bone age and skeletal maturity and its comparison to chronological age is an important task in the medical environment for the diagnosis of pediatric endocrinology, orthodontics and orthopedic disorders, and legal environment
A. Dallora, P. Anderberg, Ola Kvist, E. Mendes, Sandra Diaz Ruiz, J. Sanmartin Berglund   +5 more
semanticscholar   +1 more source

Aging and Mechanoadaptive Responsiveness of Bone [PDF]

Current Osteoporosis Reports, 2019
Abstract Purpose of Review Osteoporosis is an age-related disorder characterized by bone loss and increased fracture susceptibility. Whether this is due to reduced loading in less active elderly individuals or inherent modifications in bone cells is uncertain.
Behzad Javaheri, Andrew A. Pitsillides
openaire   +4 more sources

Application Status and Research Progress of Imaging Assessment of Skeletal Maturity in Adolescents and Children

Xiehe Yixue Zazhi
Skeletal maturity can reflect an individual's developmental status and predict their future growth potential, provide clinicians with valuable diagnostic information. In recent years, significant progress has been made in imaging techniques for assessing
SUN Yuxin, GUO Xiaoyuan, ZHENG Xueqing, CHEN Shi, YANG Hongbo, PAN Hui   +5 more
doaj   +1 more source

Excessive growth hormone expression in male GH transgenic mice adversely alters bone architecture and mechanical strength [PDF]

, 2015
Patients with acromegaly have a higher prevalence of vertebral fractures despite normal bone mineral density (BMD), suggesting that GH overexpression has adverse effects on skeletal architecture and strength. We used giant bovine GH (bGH) transgenic mice
Chavassieux, P, Chenu, C, Hopkinson, M, Javaheri, B, Kopchick, J, Korbonits, M, Lim, SV, List, E, Marenzana, M, Pereira, M, Roux, J   +10 more
core   +1 more source