Results 71 to 80 of about 1,124,156 (362)

A case of chronic recurrent multifocal osteomyelitis associated with Crohn's disease [PDF]

, 2015
Chronic recurrent multifocal osteomyelitis (CRMO) is an auto-inflammatory bone disease of unknown etiology, most commonly affecting the metaphysis of long bones, especially the tibia, femur and clavicle. The clinical spectrum varies from self-limited uni-
De Baets, Frans, Dehoorne, Jo, Van Biervliet, Stephanie, van Ommen, Christi, Van Winckel, Myriam, Vande Velde, Saskia   +5 more
core  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Consequences of daily administered parathyroid hormone on myeloma growth, bone disease, and molecular profiling of whole myelomatous bone. [PDF]

PLoS ONE, 2010
Induction of osteolytic bone lesions in multiple myeloma is caused by an uncoupling of osteoclastic bone resorption and osteoblastic bone formation.
Angela Pennisi, Wen Ling, Xin Li, Sharmin Khan, Yuping Wang, Bart Barlogie, John D Shaughnessy, Shmuel Yaccoby   +7 more
doaj   +1 more source

Material and Structural Aspects of Bone in Osteogenesis Imperfecta [PDF]

, 2016
Bone fragility is a fundamental problem in individuals with osteogenesis imperfecta (OI). The mechanisms behind this fragility, however, are not yet well understood. Multiple factors appear to contribute to the increased fracture risk in OI.
Albert, Carolyne, Harris, Gerald F, Jameson, John, Smith, Peter   +3 more
core   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Calcium phosphate crystal forms in human jaw bones of changed osteoporotic structure [PDF]

Stomatološki glasnik Srbije, 2011
Introduction. Calcium phosphates are chemical compounds that can be found in various forms within nature, as well as in human jaws and bones. The aim of this study was to assess the structure of solid chemical compounds which form the structure of ...
Poštić Srđan D.
doaj   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Accumulation of Toxic Elements in Bone and Bone Marrow of Deer Living in Various Ecosystems. A Case Study of Farmed and Wild-Living Deer

Animals, 2020
The aim of the study was to determine the concentrations of toxic elements accumulated in the bone marrow and bones (Cervus elaphus). The studies were carried out on two groups of young stags: farmed (n = 6) and wild (n = 9).
Katarzyna Tajchman, Aleksandra Ukalska-Jaruga, Marek Bogdaszewski, Monika Pecio, Katarzyna Dziki-Michalska   +4 more
doaj   +1 more source

Cancellous bone and theropod dinosaur locomotion. Part II—a new approach to inferring posture and locomotor biomechanics in extinct tetrapod vertebrates [PDF]

, 2018
This paper is the second of a three-part series that investigates the architecture of cancellous bone in the main hindlimb bones of theropod dinosaurs, and uses cancellous bone architectural patterns to infer locomotor biomechanics in extinct non-avian ...
Abourachid, Abourachid, Adachi, Alexander, Allen, Allen, Allmendinger, Amson, Anderson, Anderson, Andrada, Attene, Barak, Barak, Beaupré, Beer, Bell, Bergmann, Bergmann, Biewener, Biewener, Bishop, Bishop, Bishop, Bishop, Bishop, Blob, Bona, Bonnan, Bonnan, Boyle, Brassey, Bright, Bright, Bryant, Butcher, Calow, Campoli, Cardozo, Carey, Carrano, Carrano, Carrano, Carter, Carter, Chadwick, Charles, Chinsamy-Turan, Christen, Christen, Christen, Christen, Coelho, Cowin, Currey, Delp, Delp, Dumont, Erickson, Fajardo, Fernandez, Fischer, Gatesy, Gatesy, Gatesy, Gatesy, Gefen, Geraldes, Geraldes, Giarmatzis, Giddings, Gilbert, Goetz, Goldstein, Gosnell, Griffin, Grossi, Guldman, Haines, Hayes, Houssaye, Hudson, Hudson, Huiskes, Hutchinson, Hutchinson, Hutchinson, Hutchinson, Hutchinson, Hutchinson, Hutchinson, Hébert, Jacobs, Jacobs, Jacobson, Jang, Jang, Jang, Kabel, Kambic, Kazemi, Kivell, Koch, Lamas, Lanyon, Lanyon, Lerner, Liao, Lovejoy, Lovejoy, MacLatchy, Maga, Main, Marsh, Martelli, Matarazzo, McGowan, McHenry, Medler, Miller, Modenese, Muir, Mullender, Odgaard, O’Neill, Page, Patak, Pauwels, Paxton, Pedotti, Phillips, Polk, Pontzer, Radin, Rankin, Reed, Regnault, Reilly, Ren, Richmond, Roberts, Rose, Rubenson, Rubenson, Rudman, Ruimerman, Ryan, Ryan, Ryan, Schaller, Sheffield, Smith, Steele, Stoessel, Stops, Su, Su, Sverdlova, Taylor, Tsegai, Tsubota, Tsubota, Turner, Turner, Turner, Ulrich, Valente, van Arkel, Van Der Meulen, van der Meulen, Vander Sloten, Verner, Volpato, Wang, Wink, Winter, Witte, Wolff, Wroe, Zadpoor, Zinoviev   +180 more
core   +2 more sources

Hyperprolactinemia and bone

Pituitary, 2020
Prolactin (PRL) has direct and indirect effects on bone metabolism. Experimental studies showed that in the presence of high PRL levels bone resorption was increased as well as bone formation was suppressed. Increased PRL levels in humans caused a reduction in sex hormone levels which turn may have detrimental effects on bone.
di Filippo L., Doga M., Resmini E., Giustina A.   +3 more
openaire   +4 more sources