Results 71 to 80 of about 5,337,728 (405)
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Influence of zoledronic acid and low-intensity laser on collagen fibers during the bone repair process [PDF]
Acta Cirúrgica BrasileiraPurpose: To evaluate collagen fibers during the bone repair process in critical defects created in the tibias of rats, treated with zoledronic acid (AZ) associated with low-level laser therapy (LLLT).
Paola Aguilar +4 more
doaj +1 more source
Evolutionary patterns of bone histology and bone compactness in xenarthran mammal long bones. [PDF]
PLoS ONE, 2013 Bone microstructure reflects physiological characteristics and has been shown to contain phylogenetic and ecological signals. Although mammalian long bone histology is receiving increasing attention, systematic examination of the main clades has not yet ...
Fiona R Straehl +4 more
doaj +1 more source
American Journal of Human Genetics, 2002 Osteoporosis is a complex disease that affects >10 million people in the United States and results in 1.5 million fractures annually. In addition, the high prevalence of osteopenia (low bone mass) in the general population places a large number of people
R. D. Little +34 more
semanticscholar +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Validation of a 3D-printed human temporal bone model for otology surgical skill training
World Journal of Otorhinolaryngology-Head and Neck Surgery, 2021 Hypothesis: Three-dimensional (3D) printed temporal bones are comparable to cadaveric temporal bones as a training tool for otologic surgery. Background: Cadaveric temporal bone dissection is an integral part of otology surgical training.
Wade W. Chien +2 more
doaj
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
Bone Marrow Cell Recognition: Training Deep Object Detection with A New Loss Function [PDF]
arXiv, 2021 For a long time, bone marrow cell morphology examination has been an essential tool for diagnosing blood diseases. However, it is still mainly dependent on the subjective diagnosis of experienced doctors, and there is no objective quantitative standard.
arxiv
Quantifying Changes in the Spatial Structure of Trabecular Bone [PDF]
International Journal of Bifurcation and Chaos, 22(2), 2012, 2010 We apply recently introduced measures of complexity for the structural quantfication of distal tibial bone. For the first time, we are able to investigate the temporal structural alteration of trabecular bone. Based on four patients, we show how bone may alter due to temporal immobilisation.
arxiv +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source