Results 81 to 90 of about 5,557,011 (339)

Bone mineral density and body composition in girls with idiopathic central precocious puberty before and after treatment with a gonadotropin-releasing hormone agonist

open access: yesClinics, 2012
OBJECTIVES: Idiopathic central precocious puberty and its postponement with a (gonadotropin-releasing hormone) GnRH agonist are complex conditions, the final effects of which on bone mass are difficult to define. We evaluated bone mass, body composition,
Sandra B. Alessandri   +8 more
doaj   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

Bone Mineral Density in Patients Receiving Anticonvulsant Drugs

open access: yesTürk Osteoporoz Dergisi, 2002
The study was carried out to determine possible effects of anticonvulsant drugs on bone mineral density. Twenty two patients with epilepsy who have been receiving anticonvulsant drugs and also 22 healthy controls were included in the study.
Kadir Yıldırım   +4 more
doaj  

Relative Contribution of Trabecular and Cortical Bone to Primary Implant Stability: An In vitro Model Study

open access: yesJournal of Pharmacy and Bioallied Sciences
Background: Primary implant stability is a crucial factor for the successful osseointegration and long-term success of dental implants. The contribution of trabecular and cortical bone to primary implant stability is not well understood.
Trinanjali Bera   +7 more
doaj   +1 more source

Impact of degenerative radiographic abnormalities and vertebral fractures on spinal bone density of women with osteoporosis

open access: yesSão Paulo Medical Journal, 2002
CONTEXT: Measurements of bone density taken by dual-energy x-ray absorptiometry are the most accurate procedure for the diagnosis of osteoporosis.
Lúcia Costa Paiva   +4 more
doaj   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Effects of raloxifene on bone mineral density, serum cholesterol concentrations, and uterine endometrium in postmenopausal women.

open access: yesNew England Journal of Medicine, 1997
BACKGROUND Long-term estrogen therapy can reduce the risk of osteoporotic fracture and cardiovascular disease in postmenopausal women. At present, however, these beneficial effects are not separable from undesirable stimulation of breast and endometrial ...
P. Delmas   +7 more
semanticscholar   +1 more source

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

open access: yesFEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski   +13 more
wiley   +1 more source

Bone Mechanical Properties in Healthy and Diseased States.

open access: yesAnnual Review of Biomedical Engineering, 2018
The mechanical properties of bone are fundamental to the ability of our skeletons to support movement and to provide protection to our vital organs.
E. Morgan, G. Unnikrisnan, A. Hussein
semanticscholar   +1 more source

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