Results 101 to 110 of about 9,532 (200)

Anti‐PSMA Functionalized PLGA‐PEG Nanoparticles for Active Targeting of LnCap Cells and Controlled Release of Docetaxel in Prostate Cancer

open access: yesNano Select, EarlyView.
Design of experiments was used to optimize docetaxel‐loaded PLGA‐PEG nanoparticles that were fabricated by nanoprecipitation using a microfluidics technique. The nanoparticles were functionalized with an antibody to target prostate‐specific membrane antigen receptor on LnCap prostate cancer cells.
Divesha Essa   +2 more
wiley   +1 more source

Lions as Bone Accumulators? Exploring Multi‐Predator Contributions to the Olduvai Carnivore Site (OCS) (Tanzania) Through AI and Metric Analyses

open access: yesInternational Journal of Osteoarchaeology, EarlyView.
ABSTRACT Lions (Panthera leo) are apex predators with a well‐documented influence on ecological dynamics, yet their potential role as bone‐accumulating agents remains poorly understood and often debated. Previous taphonomic studies have largely attributed bone accumulations in African savannah ecosystems to other carnivores, such as spotted hyenas ...
Blanca Jiménez‐García   +2 more
wiley   +1 more source

Bone Health and Endocrine Therapy with Ovarian Function Suppression in Premenopausal Early Breast Cancer: A Real-Life Monocenter Experience with Denosumab. [PDF]

open access: yesCurr Oncol
Rotondi A   +18 more
europepmc   +1 more source

Large, rugged and remote: The challenge of wolf–livestock coexistence on federal lands in the American West

open access: yesPeople and Nature, EarlyView.
Abstract The expansion of grey wolves (Canis lupus) across the western United States, including on public lands used for extensive livestock grazing, requires tools and techniques for reducing wolf–livestock conflict and supporting coexistence. We examined approaches used on forested lands managed by the U.S.
Robert M. Anderson   +3 more
wiley   +1 more source

The importance of wild meat and freshwater fish for children's nutritional intake in the Congo Basin

open access: yesPeople and Nature, EarlyView.
Abstract Wild meat and freshwater fish are widely consumed in the Congo Basin, but in some areas, they are at risk of disappearing due to unsustainable hunting and fishing and changes in their habitat. Wild meat is also at risk of being eliminated from local diets due to potential policy changes such as wild meat bans.
Amy Ickowitz   +6 more
wiley   +1 more source

Proteome‐Wide Analysis of Palmitoylated Proteins in Macrophages Reveals Novel Insights Into Early Immune Signaling

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Protein S‐palmitoylation, a reversible lipid modification, plays critical roles in regulating protein function and localization. However, its comprehensive role in the rapid reprogramming of macrophages during early immune responses remains incompletely understood.
Hyojung Kim   +4 more
wiley   +1 more source

Case Report: Osteomyelitis in a giant panda (<i>Ailuropoda melanoleuca</i>). [PDF]

open access: yesFront Vet Sci
Wang C   +12 more
europepmc   +1 more source

Lipid Nanoparticles Delivering ClpP‐mRNA Suppress Pyroptosis and Senescence in Intervertebral Disc Degeneration via mTOR/BNIP3‐Activated Mitophagy

open access: yesRare Metals, EarlyView.
ABSTRACT Intervertebral disc degeneration (IDD) is a predominant cause of low back pain, significantly impacting quality of life. Mitochondrial fitness is essential in the progression of IDD, as it regulates cellular senescence and pyroptosis. This study investigates the role of mitochondrial caseinolytic protease P (ClpP) in alleviating senescence and
Kun Wang   +7 more
wiley   +1 more source

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